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Traditional Chinese medicine composition of pseudo-ginseng and sea-buckthorn and preparation method of composition

A composition and technology of sea buckthorn, applied in the directions of drug combination, pharmaceutical formula, plant raw material, etc., can solve the problems of stimulating gastric mucosa, long course of treatment, inhibiting heart function, etc., and achieve the effect of controllable quality and good curative effect.

Inactive Publication Date: 2014-01-15
TIANJIN TIANSHI BIOLOGICAL DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since coronary heart disease is a chronic disease, the course of drug treatment is long, and long-term use of drugs can cause serious adverse reactions such as headache, cough, stimulation of gastric mucosa, hypotension, inhibition of heart function, and damage to liver and kidney functions.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0075] Active components are extracted from raw materials according to the following percentages by weight: 10% seabuckthorn and 90% Panax notoginseng.

[0076] Take seabuckthorn and notoginseng medicinal materials, grind them, add ethyl acetate and 70% ethanol at a volume ratio of 1:2, heat and extract twice, the first time for 1 hour, the second time for 1 hour, and the filtrates are combined to obtain extract I. Add 70% ethanol to the dregs, heat and reflux to extract twice, the first time is 0.5 hours, the second time is 0.5 hours, the filtrates are combined to obtain the extract II, the combined extracts I and II are concentrated into extracts, and 50% ethanol is used to dissolve and extract Ointment, using macroporous resin AB-8 to separate it, first eluting with water to obtain eluent I; then eluting with 50% ethanol, and then eluting with 90% ethanol, the elution flow rate is 1BV / h, The eluent II was obtained, recovered, concentrated under reduced pressure, and dried t...

Embodiment 2

[0079] Active components are extracted from raw materials according to the following percentages by weight: 85% seabuckthorn and 15% Panax notoginseng.

[0080] Take seabuckthorn and notoginseng medicinal materials, pulverize them, add ethyl acetate and 70% ethanol at a volume ratio of 1:2, heat and extract twice, the first time is 3 hours, the second time is 2 hours, the filtrates are combined to obtain extract I, Add 70% ethanol to the medicinal dregs, heat and reflux to extract twice, the first time is 1.5 hours, the second time is 1 hour, the filtrates are combined to obtain the extract II, the combined extracts I and II are concentrated into an extract, and dissolved in 50% ethanol for extraction Ointment, using macroporous resin X-5 to separate it, first eluted with water to obtain eluent I; then eluted with 60% ethanol, and then eluted with 95% ethanol, the elution flow rate is 4BV / h, The eluent II was obtained, recovered, concentrated under reduced pressure, and dried ...

Embodiment 3

[0083] Active ingredients are extracted from raw materials according to the following percentages by weight: 15% seabuckthorn and 85% Panax notoginseng.

[0084] Take seabuckthorn and notoginseng medicinal materials, pulverize them, add ethyl acetate and 70% ethanol at a volume ratio of 1:2, heat and extract twice, the first time is 1.5 hours, the second time is 1.5 hours, and the filtrates are combined to obtain extract I. Add 70% ethanol to the medicinal dregs, heat and reflux to extract twice, the first time for 1 hour, and the second time for 1 hour, the filtrates are combined to obtain the extract II, the combined extracts I and II are concentrated into an extract, and dissolved in 50% ethanol for extraction Ointment, using macroporous resin AB-8 to separate it, first eluting with water to obtain eluent I; then eluting with 55% ethanol, and then eluting with 95% ethanol, the elution flow rate is 3BV / h, The eluent II was obtained, recovered, concentrated under reduced pres...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition of pseudo-ginseng and sea-buckthorn. The composition comprises the following active pharmaceutical ingredients by weight percent: 10-85% of sea-buckthorn and 15-90% of pseudo-ginseng. The invention also discloses a preparation method of the traditional Chinese medicine composition. The preparation method comprises the steps of extracting the active ingredients and preparing the finished product according to the formula. The traditional Chinese medicine composition makes the best of the treatment effects of the active pharmaceutical ingredients on cardiovascular diseases, adopts scientific matching, generates synergistic effects, has better curative effects and more controllable quality than traditional sea-buckthorn extract preparations and is suitable for industrial production.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating cardiovascular diseases and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] With the continuous improvement of people's living standards, changes in diet structure, population aging is becoming more and more obvious, and the incidence of coronary heart disease is increasing day by day. Coronary heart disease is a heart disease caused by narrowing of the lumen caused by coronary atherosclerosis, which causes myocardial blood supply and oxygen supply disturbance, and is known as the "world killer". As far as the whole world is concerned, coronary heart disease has become one of the most serious diseases threatening human health in the past half century, and it is the main cause of death in the United States and some industrialized countries. According to the statistics of the World Health Organization, 24....

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/258A61P9/00A61P9/10
Inventor 崔卜东贾林
Owner TIANJIN TIANSHI BIOLOGICAL DEV
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