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Schisandra chinensis dl-tetrahydropalmatine preparation

A technology of schisandrin B and preparation, which is applied in the field of biomedicine and can solve the problems of unsatisfactory liver protection products and unsatisfactory effects

Inactive Publication Date: 2014-01-22
苏州天南星生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] With the continuous change of people's living standards and lifestyles, various traditional Chinese medicine liver protection products have emerged as the times require, but most of them have shortcomings such as unsatisfactory effects, and there is no very satisfactory liver protection product so far.

Method used

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  • Schisandra chinensis dl-tetrahydropalmatine preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Example 1: Schisandra B preparation, its raw materials and parts by weight are: 10 parts of Schisandra B, 100 parts of soybean lecithin, adding appropriate amount of auxiliary materials to make capsules, tablets, granules, etc.

Embodiment 2

[0015] Embodiment 2: to CCl 4 Protective effect of induced chemical liver injury in mice

[0016] The mice were divided into random groups, 10 in each group, administered continuously for 7 days, and subcutaneously injected with 0.5% CCl 1 hour after the last administration 4 Oil solvent 0.1mg / kg was used to replicate the acute liver injury model, blood was collected from the orbital venous plexus 16 hours later, the serum was separated, and the contents of ALT and AST in the serum were determined. T-test test was carried out between the indexes of each administration group and the model group.

[0017] Table 1. For CCl 4 Protective effect of induced chemical liver injury in mice

[0018]

[0019] Compared with the blank control group, # p* p<0.05

[0020] Tests have shown that the serum AST and ALT values ​​of the drug-administered group of the present invention are significantly lower than those of the model control group, and are close to those of the blank contro...

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Abstract

The invention discloses schisandra chinensis dl-tetrahydropalmatine preparation. Main raw materials of the preparation are schisandra chinensis dl-tetrahydropalmatine and granulesten. The preparation has exact curative effect on chemical liver injury.

Description

technical field [0001] The invention belongs to the field of biomedicine, and in particular relates to a schisandra B preparation. Background technique [0002] In my country, there are more than ten million patients with liver disease caused by factors such as chemical drugs, pathogens or excessive drinking. Hepatitis is one of the main diseases that seriously threaten the health of our people. Hepatitis is a general term for inflammatory diseases of the liver. In the clinical treatment of hepatitis, comprehensive treatment is generally adopted, that is, antiviral drugs, immune enhancers and liver-protecting drugs. Antiviral drugs and immune enhancers focus on clearing the virus in the body, and liver protection drugs focus on the recovery of the liver. At present, there are very few truly effective antiviral drugs, such as lamivudine, famciclovir and other anti-HBV drugs, which cannot completely suppress the virus. The currently recognized effective immune enhancer again...

Claims

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Application Information

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IPC IPC(8): A61K31/685A61K36/48A61P1/16A61K31/36
Inventor 不公告发明人
Owner 苏州天南星生物科技有限公司
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