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Coix seed bran extract and its application

A technology of extract and Coix seed, applied in the field of Coix seed bran extract, can solve the problem that different applications of Coix seed extract are still to be developed, etc., and achieve the effect of enhancing radiation curative effect and reducing radiation dose

Inactive Publication Date: 2017-05-31
JOBEN BIO MEDICAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Although many uses of coix seed have been reported, the different applications of the extract of coix seed are still to be developed

Method used

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  • Coix seed bran extract and its application
  • Coix seed bran extract and its application
  • Coix seed bran extract and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0093] Example 1: Animal Model

[0094] Drugs and reagents: Yiyizi was purchased from farmers in Taichung County, Taiwan, and planted in 2009 as Taichung Shuenyu no.4 (TCS4) Yiyi (C. lachrymajobi L.).

[0095] Alcohol extract (A) with 1 to 7 carbon numbers of coix seed bran: remove the shell and seed coat of coix seed with a grinder, then grind the coix bran into powder, soak in three times the amount of 95 % ethanol (w / v), extracted under ultrasonic vibration for 24 hours. After mixing three extracts, concentrate under reduced pressure at 50° C. to obtain ethanol extract of coix bran.

[0096] Carbon dioxide supercritical fluid extract of coix seed bran (B): use a grinder to remove the shell and seed coat of coix seed bran, then grind the coix bran into powder, put the coix seed bran into the stainless steel extraction tank, and then put The inner tank is put into the extraction tank of the supercritical extraction equipment. The extraction conditions are as follows: extra...

Embodiment 2

[0108] Example 2: Human trials for alleviating the side effects of radiotherapy in patients with breast cancer

[0109] Take two coix seed capsules (test group, extract A: extract B ratio of 1:4) or olive oil capsules (control group) (500mg / capsule) after breakfast and dinner every day, four capsules a day.

[0110] This clinical trial adopts a prospective, randomized and double-blind design and is divided into a test group and a control group. It is divided into two stages: the first stage is to test the response of Coix Capsules in ordinary people, and take two capsules each day after breakfast and dinner ( 500mg / capsule), four capsules a day for four consecutive weeks. Blood test before the test: including general blood, liver function (including GOT, GPT), kidney function (including BUN, CRTN), general function (including cholesterol, HDL, LDL, TG, AC-sugar), etc. After four weeks of continuous use, the same blood test was taken again. After confirming that there were no ...

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Abstract

The present invention provides an extract of coix seed bran, which includes an alcohol extract (A) with a carbon number of 1 to 7 from coix seed bran and a carbon dioxide supercritical fluid extract (B) of coix seed bran. Preferably, the coix seed bran extract has the effect of treating skin and / or subcutaneous tissue diseases.

Description

technical field [0001] The present invention relates to coix seed bran extract and its use; specifically, it is used for treating skin and / or subcutaneous tissue diseases. Background technique [0002] The skin is the largest organ in the human body and the main barrier between the body and the environment, providing the first line of defense against microbial pathogens and physical and chemical stress or stimulation. The skin not only provides physical and chemical protection, but also serves as an immune organ that can effectively induce passive and active immune responses, thereby protecting the human body. [0003] From the outside to the inside, the skin can be divided into three layers: the epidermis, the dermis and the subcutaneous tissue. The outermost layer of the epidermis is responsible for the protective function; Intertwined into a support network, and can make blood vessels, lymphatic vessels, nerves, sebaceous glands, sweat glands and hair follicles distribut...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8994A61K8/9794A61P17/00A61P17/02A61P17/14A61P17/04A61P17/10A61P17/16A61P9/14A61Q19/00A23L33/00
Inventor 曾焕中黄乔志贾铜安
Owner JOBEN BIO MEDICAL
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