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A preparation for treating periodontitis with a combination of effective parts of Scutellaria baicalensis and Rhizoma Drynariae

A technology of effective parts and Rhizoma Drynaria, applied in the direction of medical preparations with non-active ingredients, medical preparations containing active ingredients, anti-inflammatory agents, etc., can solve the problem of stability, controllability, and lack of pharmacology Research and other issues, to achieve a wide range of clinical application prospects, no toxic and side effects, and significant curative effect

Active Publication Date: 2017-12-26
XI AN JIAOTONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, these prescriptions lack the support of pharmacological research, and from the perspective of preparation quality, the stability and controllability of such drugs are also difficult to achieve

Method used

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  • A preparation for treating periodontitis with a combination of effective parts of Scutellaria baicalensis and Rhizoma Drynariae
  • A preparation for treating periodontitis with a combination of effective parts of Scutellaria baicalensis and Rhizoma Drynariae
  • A preparation for treating periodontitis with a combination of effective parts of Scutellaria baicalensis and Rhizoma Drynariae

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] The ingredients by weight of raw materials in this example are: 15 parts of ethanol extract of Scutellaria baicalensis (baicalein 80%) and 8 parts of drynariae water extract (30.71% of naringin); 1 part of gelatin and 2 parts of glycerin.

Embodiment 2

[0038] The ingredients by weight of raw materials in this example are: 14 parts of ethanol extract of Scutellaria baicalensis (baicalein 80%) and 9 parts of drynariae water extract (30.71% of naringin); 1 part of gelatin and 2 parts of glycerin.

Embodiment 3

[0040] The ingredients by weight of raw materials in this example are: 13 parts of ethanol extract of Scutellaria baicalensis (80% baicalein) and 10 parts of drynariae water extract (30.71% naringin); 1 part of gelatin and 2 parts of glycerin.

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Abstract

Scutellaria baicalensis and rhizoma drynariae effective part compatibility prescription for treating periodontitis, its raw material components include: 10‑15 parts of water extract of scutellaria baicalensis effective parts containing more than 80% baicalein and 30.71% naringin 5‑10 parts of the water extract of drynaria effective parts above are made into "Qinbu Guchi Capsules" for systemic administration; or add hydroxyethyl cellulose, concentrated glycerin, polyacrylic acid resin and other auxiliary materials to make a new type of external application Long-acting traditional Chinese medicine compound ointment "Qinbu Guchi Ointment", the syringe-style administration method is easy to operate in the periodontal pocket. The invention has good therapeutic effect on periodontitis. The invention has the characteristics of small prescription, remarkable curative effect and no toxic and side effects. Especially when applied locally, the anti-inflammatory effect of long-term use is similar to that of minocycline hydrochloride ointment (Paileo), but the bone formation effect is obviously better than Paleo. New dosage forms of oral Chinese patent medicines with ease of use.

Description

technical field [0001] The present invention relates to the application and preparation of a kind of Chinese patent medicine, in particular to a preparation for treating periodontitis with a combination prescription of effective parts of Scutellaria baicalensis and Rhizoma Drynariae, which can be administered by local injection into periodontal pocket or systemic oral administration. , for the treatment of periodontitis. Background technique [0002] Periodontitis is the disease with the highest incidence rate in the oral field, and it is also a difficult disease in the field of oral medicine. It has become the main cause of tooth loss in adults. At the same time, it also induces many systemic diseases, such as rheumatism, heart disease, blood disease, diabetes, etc., and is considered to be the third biggest killer threatening human health after cancer and cardiovascular and cerebrovascular diseases. Periodontitis is a chronic bacterial infectious disease. The destruction ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7048A61K31/352A61K36/539A61K36/11A61K47/38A61K47/32A61K47/10A61P1/02A61P29/00
Inventor 李昂王嗣岑苟建重孙俊毅
Owner XI AN JIAOTONG UNIV
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