38results about How to "Efficient treatment effect" patented technology

The invention discloses composite nano-particles used in inorganic photodynamic therapy, and a preparation method thereof. According to the invention, nano-particles with an up-conversion luminescence property under infrared light excitation are composed with TiO2, ZrO2 or Zr-Ti-O nano-particles with good biocompatibility with cell killing property under ultraviolet light irradiation, such that composite nano-particles are prepared. The composite nano-particles can be adopted as a near-infrared-light-excited novel inorganic photodynamic therapy reagent, and has characteristics of good body tissue penetration capacity, good safety, and no damage. Because the particles have nano-grade dimensions, the retention time of the nano-particles in bodies is long, and the nano-particles have stability better than that of traditional organic photo-sensitizers. Therefore, the nano-particles have important application potential in photodynamic therapies of malignant tumors.

The purpose of the invention is to provide a Pudilan children's antiviral oral pellet gel and a preparation method thereof. The preparation method comprises the following steps: adopting a gel matrix, extracting Radix Scutellariae, Herba Taraxaci, Corydalis bungeana Turcz. and isatis root, preparing pellets by using extracted effective components, and uniformly dispersing the pellets in a gel. The prepared gel can be a solid gel, a semisolid gel or a xerogel. The method effectively covers the bad smell of medicines, solves the mouthfeel problem of the medicines, and allows the sweet oral pellet gel loved by children to be prepared, and the sweet and smooth mouthfeel of the oral pellet gel makes children easily take the medicine. Traditional Chinese medicines are combined with the gel dosage form to improve the children's administration long-term single dosage form, and the oral pellet gel has the efficacies of heat clearing, detoxification, antibiosis and inflammation prevention, and also has the advantages of high content of the effective component, small administrating dosage, stable preparation and good curative effect.

The invention provides an amphiphilic graft copolymer based on hyaluronic acid, and a preparation method and application of the amphiphilic graft copolymer. The copolymer disclosed by the invention comprises hyaluronic acid (HA) serving as a parent skeleton, deoxycholic acid (DCA) grafted on the skeleton, a methoxy polyethylene glycol (mPEG) unit and an N-acetyl-L-cysteine (NAC) group. The invention also provides the preparation method of the copolymer. According to the method, the copolymer is prepared by modifying HA with mPEG, DCA and NAC. The invention also provides a hemostatic sponge, adrug carrier and a pharmaceutical composition prepared from the copolymer. The copolymer is good in biocompatibility, high in water absorption speed and capable of achieving active-and-passive dual targeting and redox conversion, and therefore, the copolymer can be used for preparing the hemostatic sponge capable of realizing rapid water absorption and an anti-cancer drug release carrier, realizesblood circulation prolonging, high uptake and rapid drug release of drugs, effectively increases drug concentrations in tumor cells and has good application prospects.

The invention discloses a preparation method of panax quinquefolius raw powder tablets, and belongs to the technical field of health care products. The method comprises nine steps: sorting, cleaning, drying, crushing, grinding, granulating, mixing, tabletting and sterilizing. The panax quinquefolius raw powder tablets do not contain any auxiliary materials; the bioavailability of product is increased; the product is more convenient to use, with longer guarantee period, lower processing cost, good dispersibility, miscibility and absorbability, thus the effective constituents of panax quinquefolius enter human body quickly; the original taste is reserved, and the health care function is increased; moreover, the dosage can be exponentially reduced, thereby effectively increasing utilization ratio of rare resources.

The invention discloses a shockwave treatment apparatus. The apparatus comprises a control cabinet, a universal adjustment bracket, a shockwave therapy device and a penis fixing device; one end of theuniversal adjustment bracket is in pivoted fit with the control cabinet, the other end of the universal adjustment bracket is in pivoted fit with the input end of the shockwave therapy device, and the penis fixing device is mounted at the output end of the shockwave therapy device; and the control cabinet controls the shockwave therapy device to intake or exhaust air in order to make the shockwave therapy device generate shockwaves or return. The universal adjustment bracket is arranged to reach the relative fixation of the shockwave therapy device, the direction and the angle are adjusted asneeded, and the penis is clamped by the penis fixing device to realize the long-time relative fixation of the shockwave therapy device and the penis in order to ensure the stable and efficient therapy effect, so the manpower is saved, and inconveniences in the therapy process are reduced.

The invention provides an implant as well as a preparation method and application thereof. The implant comprises an implant suture and a drug coating arranged on the surface of the implant suture, wherein the drug coating comprises a drug and a controlled release factor. According to the implant provided by the invention, the implant can achieve an effect of quantitatively and slowly releasing the drug so as to eliminate or reduce pain, inflammatory swelling, infection and other risks in the implantation process on the basis of ensuring that the implant can be smoothly implanted into the human body, and a high-efficiency treatment effect can be achieved at a small dosage; moreover, by modifying the surface of the implant suture, good adhesion is maintained between the implanted implant suture and the drug coating. The drug coating is sprayed onto the implant suture in a spray manner, so that the drug on the surface of the implant suture can be uniformly dispersed, and convenience is brought to uniform and stable release of the drug. The implant is simple in preparation method, readily available in raw materials and easy to realize and has excellent effects in aspects such as inflammation control and swelling subsidence.

The invention relates to a preparation utilizing a compatibility prescription of the effective parts of rhizoma coptidis and rhizoma drynariae in treatment of periodontitis. The preparation comprises the following components by mass: 10-15 parts of a rhizoma coptidis effective part's water extract with a berberine content of more than 80%; and a rhizoma drynariae effective part's water extract with a naringin content of more than 30.71%. The preparation can be prepared into a ''rhizoma coptidis-rhizoma drynariae tooth strengthening capsule'' for systemic administration, or can be added with hydroxyethyl cellulose, concentrated glycerol, polyacrylic resin and other auxiliary materials to make a novel topical Chinese medicinal long-acting compound ointment ''rhizoma coptidis-rhizoma drynariae tooth strengthening ointment'', and a syringe administration mode is easy for operation at local parts of a periodontal pocket. With a good therapeutical effect on periodontitis, the preparation provided by the invention has the characteristics of small prescription, significant curative effect, no toxic or side effect. Especially in local application, after long-term use, the anti-inflammatory effect is similar to that of minocycline hydrochloride ointment (Periocline), but the osteogenic effect is obviously superior to that of Periocline. Thus, the preparation is a novel oral Chinese patent medicine with long-term efficacy and usability similar to western medicines.

The invention relates to a slow-release system of a supramolecular structure, in particular to a drug carrier system based on supramolecular recognition self-assembly as well as a preparation method and an application thereof. The drug carrier system provided by the invention is formed by self-assembling beta-glucan and a high-molecular compound with positive charges; wherein the high-molecular compound is selected from polysaccharides, polypeptides or compositions or polymers of polysaccharides and polypeptides. The drug carrier system provided by the invention has important application valuein the aspects of active drug wrapping and delivery.

The invention discloses a traditional Chinese medicine composition for treating or treating bedsores in an adjuvant mode. The traditional Chinese medicine composition is mainly prepared from the following traditional Chinese medicines in parts by weight: 1-5 parts of radix ginseng, 1-10 parts of radix notoginseng, 1-10 parts of radix astragali, 1-5 parts of radix angelicae sinensis, 1-10 parts offlos carthami, 1-10 parts of radix rhei officinale, 1-10 parts of rhizoma polygoni cuspidati, 1-10 parts of radix lithospermi, 1-5 parts of honeysuckle flowers, 1-10 parts of fructus forsythiae, 1-10parts of angelica roots, 1-5 parts of garden burnet roots, 1-10 parts of frankincense, 1-10 parts of myrrh and 10-20 parts of borneol. The drug composition disclosed by the invention adopts common rawmaterials, is simple in preparation method, and has effective and reliable treatment effect for bedsores, especially severe bedsores of grade III or higher. The drug composition disclosed by the invention is stable in property, and has no statistical significance in treatment effect difference for a light patient after being stored for a long time at a high temperature.

The invention discloses an application of the milk of a lactating woman taking Wangshi Baochi pills in treating infant diseases. In the invention, an efficient, quick, convenient and safe treatment effect can be realized on infant diseases, and related diseases of the mother and infant also can be treated at the same time.

The invention discloses a recovery plaster for promoting blood circulation to dispel blood stasis. The recovery plaster is prepared by the steps of heating sesame oil in an iron pan, adding mistletoe, adhatoda ventricosa, common gendarussa herb, angelica, Sichuan lovage rhizome, nux vomica, raw kusnezoff monkshood root, raw Sichuan aconite root, safflower, asarum, teasel root, eucommia bark, clematis root, common clubmoss herb, cassia twig, gentiana macrophylla, angelica pubescens, atractylodes, suberect spatholobus stem, Korean pine bark, datura flower and loose knot, filtering herb residue and reserving oil for later use; adding frankincense and myrrh when the oil in the pan is naturally cooled to 75 DEG C, stirring with the oil, adding viscous yellow wax, and heating over small fire to form plaster; and adding azone and chlorpheniramine when the plaster is naturally cooled to 45 DEG C, and uniformly spreading the plaster on the disinfected cotton cloth. By adopting the recovery plaster, an operation is not needed for tissue symptoms around joints; and the recovery plaster realizes quick inflammation and swelling diminishment, has quick response and short treatment course, can relieve the pain of patients and is simple and convenient to use.