The invention provides Nanxing Compound Pain Paste Cataplasma Combination, which is prepared from the following by the following weight parts: 267 grams of raw arisaema tuber, 200 grams of radix aconiti, 167 grams of cloven, 167 grams of cinnamon, 300 grams of angelica, 1250 grams of asarum, 200 grams of hemlock parsley, 125 grams of panicled swallowwort root, 83 grams of frankincense, 83 grams of myrrh, and 63 grams of borneol. The auxiliary materials used for preparing Nanxing Compound Pain Paste Cataplasma Combination are as follows by the following weight parts: 1.5kg of Np-700, 60 grams of dihydroxyaluminium aminoacetate, 60 grams of tartaric acid, 15 grams of EDTA, 6kg of glycerol, 362 grams of crosslinking polyvingypyrrolidone, 11kg of purified water, 100 grams of gelatin, 100 grams of azone, 200 grams of propylene glycol, 160 grams of methyl salicylate. By adopting the materials, 1000 pieces of cataplasma herb paste are prepared. The camphor and the borneol are in powder shape. Other medicaments ethanol extracts. The invention further provides a method used for preparing the combination. Nanxing Compound Pain Paste Cataplasma Combination carries large dosage, conserves water, preserves moisture, has excellent air permeability and skin permeability, can be removed and attached repetitively without such side effects as irritability and so on.