Preparation utilizing compatibility prescription of effective parts of rhizoma coptidis and rhizoma drynariae in treatment of periodontitis

Abstract

The invention relates to a preparation utilizing a compatibility prescription of the effective parts of rhizoma coptidis and rhizoma drynariae in treatment of periodontitis. The preparation comprises the following components by mass: 10-15 parts of a rhizoma coptidis effective part's water extract with a berberine content of more than 80%; and a rhizoma drynariae effective part's water extract with a naringin content of more than 30.71%. The preparation can be prepared into a ''rhizoma coptidis-rhizoma drynariae tooth strengthening capsule'' for systemic administration, or can be added with hydroxyethyl cellulose, concentrated glycerol, polyacrylic resin and other auxiliary materials to make a novel topical Chinese medicinal long-acting compound ointment ''rhizoma coptidis-rhizoma drynariae tooth strengthening ointment'', and a syringe administration mode is easy for operation at local parts of a periodontal pocket. With a good therapeutical effect on periodontitis, the preparation provided by the invention has the characteristics of small prescription, significant curative effect, no toxic or side effect. Especially in local application, after long-term use, the anti-inflammatory effect is similar to that of minocycline hydrochloride ointment (Periocline), but the osteogenic effect is obviously superior to that of Periocline. Thus, the preparation is a novel oral Chinese patent medicine with long-term efficacy and usability similar to western medicines.

Description

technical field [0001] The present invention relates to the application and preparation of a Chinese patent medicine, in particular to a preparation for treating periodontitis by using the compatible prescription of the effective parts of Coptis Rhizoma and Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizome. , for the treatment of periodontitis. Background technique [0002] Periodontitis is the disease with the highest incidence rate in the oral field, and it is also a difficult disease in the field of oral medicine. It has become the main cause of tooth loss in adults. At the same time, it also induces many systemic diseases, such as rheumatism, heart disease, blood disease, diabetes, etc., and is considered to be the third biggest killer threatening human health after cancer and cardiovascular and cerebrovascular diseases. Periodontitis is a chronic bacterial infectious disease. The destruction of perio...

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Problems solved by technology

[0004] However, these prescriptions lack the support of pharmacological research, and from the perspe...

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