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A preparation for treating periodontitis with a combination of effective parts of Coptidis Rhizoma and Rhizoma Drynariae

A technology of effective parts and Rhizoma Drynaria, applied in the direction of medical preparations with non-active ingredients, medical preparations containing active ingredients, anti-inflammatory agents, etc., can solve the problems of lack of pharmacological research, stability, and controllability Realization and other problems, to achieve the effects of no toxic side effects, wide clinical application prospects, and simple preparation methods

Active Publication Date: 2017-01-11
XI AN JIAOTONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, these prescriptions lack the support of pharmacological research, and from the perspective of preparation quality, the stability and controllability of such drugs are also difficult to achieve

Method used

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  • A preparation for treating periodontitis with a combination of effective parts of Coptidis Rhizoma and Rhizoma Drynariae
  • A preparation for treating periodontitis with a combination of effective parts of Coptidis Rhizoma and Rhizoma Drynariae
  • A preparation for treating periodontitis with a combination of effective parts of Coptidis Rhizoma and Rhizoma Drynariae

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] The ingredients by weight of raw materials in this example are: 15 parts of water extract of Coptis Rhizoma (80% berberine) and 8 parts of water extract of Rhizoma Drynariae (30.71% naringin); 1 part of gelatin and 2 parts of glycerin.

Embodiment 2

[0038] The ingredients by weight of raw materials in this example are: 14 parts of water extract of Coptidis rhizome (80% berberine) and 9 parts of water extract of drynariae (30.71% naringin); 1 part of gelatin and 2 parts of glycerin.

Embodiment 3

[0040] The ingredients by weight of raw materials in this example are: 13 parts of water extract of Coptis Rhizoma (80% berberine) and 10 parts of water extract of Rhizoma Drynariae (30.71% naringin); 1 part of gelatin and 2 parts of glycerin.

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Abstract

A preparation for treating periodontitis with a combination prescription of Coptidis Rhizoma and Rhizoma Drynariae effective parts, the raw material components include: 10-15 parts of water extract of Coptidis Rhizoma effective parts containing more than 80% berberine; naringin 30.71 % more than 5-10 parts of drynaria effective parts water extract; made into "Lian Bu Gu Chi Capsule" for systemic administration; or adding hydroxyethyl cellulose, concentrated glycerin, polyacrylic resin and other auxiliary materials to make a The new long-acting compound ointment of traditional Chinese medicine for external use "Lian Bu Gu Te Ointment" is easy to operate in the periodontal pocket by means of syringe administration. The invention has good therapeutic effect on periodontitis. The invention has the characteristics of small prescription, remarkable curative effect and no toxic and side effects. Especially when applied locally, the anti-inflammatory effect of long-term use is similar to that of minocycline hydrochloride ointment (Paileo), but the bone formation effect is obviously better than Paleo. New dosage forms of oral Chinese patent medicines with ease of use.

Description

technical field [0001] The present invention relates to the application and preparation of a Chinese patent medicine, in particular to a preparation for treating periodontitis by using the compatible prescription of the effective parts of Coptis Rhizoma and Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizome. , for the treatment of periodontitis. Background technique [0002] Periodontitis is the disease with the highest incidence rate in the oral field, and it is also a difficult disease in the field of oral medicine. It has become the main cause of tooth loss in adults. At the same time, it also induces many systemic diseases, such as rheumatism, heart disease, blood disease, diabetes, etc., and is considered to be the third biggest killer threatening human health after cancer and cardiovascular and cerebrovascular diseases. Periodontitis is a chronic bacterial infectious disease. The destruction of perio...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/718A61K47/38A61K47/32A61K47/10A61P1/02A61P29/00A61K36/11A61K31/4375A61K31/7048
Inventor 李昂王嗣岑苟建重孙俊毅
Owner XI AN JIAOTONG UNIV
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