The present invention discloses medicinal liquor for treating a plurality of skin diseases. The medicinal liquor is prepared through the following steps: carrying out treatments of mixing, immersing, filtering and residue removing for raw medicine and wine having a alcohol degree of 50-60 DEG, wherein the raw medicine comprises honeysuckle, hawthorn, red bean, rhubarb, cape jasmine, indian pokwees root, Chinese wolfberry root-bark, panax notoginseng, licorice root, amur corktree bark, garden radish seed, scutellaria lateriflora, Chinese starasmine stem, chrysanthemum, blackberry lily, sessile stemona root tuber and figwort. The medicinal liquor can be provided for treating eczematous dermatitis, mosquito biting, beriberi, miliaria, psoriasis vulgaris, skin itching, early skin cancerous swellings, burns and scalds, acne, exanthema, skin allergy, hand tinea unguium and foot tinea unguium, unrecognized skin affections, sores due to toxic heat and biting, herpes zoster, genital ulcer, syphilis and other skin diseases. According to the present invention, the medicinal liquor provided by the present invention is prepared from the pure traditional Chinese drugs; the medicinal liquor has effects of heat clearing and detoxication, swelling subsiding and pain relieving, wind-evil dispelling and collateral dredging, and the like; the medicinal liquor is mainly provided for treating a plurality of skin viruses; the medicinal liquor can be orally taken, or be adopted for external application so as to provide a effect of combined internal-external therapy; the medicinal liquor has characteristics of safety, no side effects, good therapeutic effect and rapid effectiveness.