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153results about How to "Low biological toxicity" patented technology

Multifunctional double-layer core-shell structure magnetic nano particle, preparation method and application thereof

The invention relates to a multifunctional double-layer core-shell structure magnetic nano particle. In the invention, a magnetic nano particle with a particle size of 1-300 nm is used as a core and coated with a double-layer shell consisting of a SiO2 layer with a thickness of 1-200 nm and a hydrolyzed silane coupling agent layer is 1-100 nm thick and comprises one or more multifunctional groups; the particle size and the shell layer thickness can be controlled through regulating the volumes, the weight ratios and the reaction time of the magnetic core, a silicon dioxide precursor, a silane coupling agent and a catalyst in a preparation process; the total particle size of the nano particle can be as small as 5-50 nm and as large as 700-800 nm; the nano particle can have superparamagnetism, paramagnetism and ferromagnetism according to the change of the magnetic core particle size; and one or more bioactive molecules can be connected into the shell layer of the magnetic nano particle or to the surface of the shell layer through a chemical method or a physical method. The invention also provides a preparation method of the multifunctional double-layer core-shell structure magnetic nano particle and application thereof. The particle preparation method has the advantages of simplicity, moderate condition, low cost and easy realization of industrial production. The nano particle can obtain different functions through connecting different bioactive molecules and can be applied to the fields of protein enrichment, biological detection, separation and purification, targeted drug carriers, cell imaging and medical imaging.
Owner:NANJING UNIV

Medical catheter and method for forming antibacterial hydrophilic coating on surface of medical catheter

The invention relates to a medical catheter and a method for forming an antibacterial hydrophilic coating on the surface of the medical catheter. The method includes the following steps of preparing graphene oxide dispersoid, dissolving hydrophilic polymers and cellulose ester in organic solvent to form a hydrophilic macromolecular solution, adding the hydrophilic macromolecular solution to the graphene oxide dispersoid in the stirring process to form an antibacterial hydrophilic macromolecular solution, soaking the catheter in a coupling agent solution after conducting surface processing on the catheter so that the surface of the catheter can be dip-coated with a coupling agent layer, soaking the catheter coated with the coupling agent layer in the antibacterial hydrophilic macromolecular solution, and preparing the medical catheter with the antibacterial hydrophilic coating after the catheter is taken out, dried and solidified. Due to the fact that the antibacterial hydrophilic coating is formed on the surface of the catheter, the coating contains graphene oxide, other hydrophilic macromolecules and other components, the catheter can have excellent antibacterial and bacteriostatic capacity, the contact angle of the catheter and water is reduced, and the surface of the catheter can have the ultra-strong lubrication effect and the bacteriostatic effect at the same time.
Owner:JIANGSU BAIHUA ELECTRONICS

Method for inhibiting peroxidase activity by using fluorescent graphene quantum dots

The invention provides a method for inhibiting peroxidase activity by using fluorescent graphene quantum dots. The method comprises the following steps: (1) adding a carbon source into a certain amount of water to prepare a mixed solution, heating the solution until the moisture is completely evaporated, transferring the solution into a high pressure reactor, heating and reacting for a period of time, dissolving the product in water, regulating the pH value of the system to be neutral by using alkali liquor, purifying the product, and drying, thereby obtaining solid graphene quantum dots; and (2) dispersing the quantum dots obtained in the step (1) in secondary distilled water, taking a proper amount of quantum dot solution and enzyme solution, adding the solution into a buffer solution, adding a color developing agent and H2O2 after a period of time, uniformly shaking the mixed solution, rapidly adding the solution into a cuvette, measuring the light absorption value of the maximum absorption wavelength of the product on an ultraviolet-visible spectrophotometer, and performing blank sample control, thereby determining the relative enzyme activity. The graphene quantum dots are prepared by adopting low-price and readily available raw materials, and the method is green and environment-friendly. The structure of the enzyme can be changed by virtue of the interaction between the graphene quantum dots and zymoprotein, and regulation of the enzyme activity is realized.
Owner:JIANGNAN UNIV

Recycling treatment system and treatment method of high-salinity high-organic-matter chemical wastewater

The invention discloses a recycling treatment system of high-salinity high-organic-matter chemical wastewater. The recycling treatment system comprises an electrocatalytic oxidation device, a halotolerant bacteria biochemical system, an MBR aerobic device, an electroosmosis unit, an ultrafilter and an RO unit, the halotolerant bacteria biochemical system comprises a halotolerant bacteria anaerobic device, a halotolerant bacteria aerobic device and a halotolerant biological aerated filter. The invention further discloses a treatment method of the high-salinity high-organic-matter chemical wastewater. By the recycling treatment system and the treatment method, the problem of recycling treatment of the high-salinity high-organic-matter chemical wastewater is solved effectively, recycling rate of water and salt is high, no wastewater is discharged basically, no solid waste is generated, generated water is high in quality, generated salt is high in purity, and water resources and salt in the high-salinity high-organic-matter chemical wastewater are recycled to greatest extent; zero discharging of wastewater in the process of enterprise production is realized, and the recycling treatment system and the treatment method have important environment benefit.
Owner:JIANGSU LASON CHEM ENVIRONMENTAL PROTECTION

Catalyst for removing nitrogen oxide through selective catalytic reduction for Ce2O3 and V2O5 double active composition diesel truck

The invention relates to a catalyst for removing nitrogen oxide through selective catalytic reduction for an automobile diesel engine adopting Ce2O3 and V2O5 double active compositions. The catalyst adopts scordierite honeycomb ceramics as a framework material, the Ce2O3 and the V2O5 as main active compositions, WO3 or MoO3 as an auxiliary catalyst composition, and TiO2 as a coating substrate, wherein the mass fraction of the main active compositions, namely the Ce2O3 and the V2O5, to the auxiliary catalyst composition WO3 or MoO3 to the coating substrate TiO2 is 1-3:6:12:85-93. The specific process comprises the following steps: preparing a TiO2 precursor solution; coating a TiO2 coating; coating an auxiliary catalyst; determining the loading of active compositions of oxides; and coating the main active compositions, namely the Ce2O3 and the V2O5. The catalyst replaces the V2O5 with high toxicity with the Ce2O3 with low toxicity, and reduces the environmental hazards of the catalyst, and the replaced catalyst has wider active temperature range, particularly greatly improves the low-temperature activity, and is particularly suitable for the traffic conditions of urban highways of China.
Owner:TIANJIN UNIV

Treatment method of PMIDA wastewater produced by using IDA method

The invention discloses a method for PMIDA wastewater produced by using an IDA method. The method comprises the following steps: regulating pH of wastewater of PMIDA mother liquid condensate to be 12 by using quick lime and liquid caustic soda; introducing steam and heating to be at 50-60 DEG C; performing alkali condensation and introducing into a biological water distributing tank; regulating pH of secondary washing water to be 1-3 and performing a micro-electrolytic reaction; adding hydrogen peroxide and performing catalytic oxidization in the presence of a surface catalyst; regulating pH to be 7.5-8; pumping wastewater into a biochemical system; using a strain which can be tolerant to 1-3 percent of salinity; degrading organic pollutants by using an ABR anaerobic I/continuous aerobic I/ABR II/continuous aerobic II method and simultaneously turning organophosphorus into orthophosphate; precipitating sludge and transporting outwards; enabling liquid supernatant to flow into a phosphorous removal reaction tank; adding coagulants and lime to be fully subjected to reaction to enable mixed liquid to flow into a phosphorous removal precipitation tank; enabling the liquid supernatant to reach the discharge standard; transporting outwards the sludge. The method is low in operation cost; effluent water is subjected to biochemical treatment so that COD completely reaches the discharge standard; after chemical phosphorous removal, the total phosphorous reaches the discharge standard, so that the pollutants are reduced to the lowest level, the chromaticity is greatly reduced, and the method has a good environmental effect.
Owner:JIANGSU LASON CHEM ENVIRONMENTAL PROTECTION

Synthetic method of cadmium telluride/cadmium sulfide/zinc sulfide quantum dots

The invention relates to a synthetic method of admium telluride/cadmium sulfide/zinc sulfide quantum dots. An inner core is an admium telluride quantum dot and is coated by cadmium sulfide and zinc sulfide in sequence. The synthetic method for the quantum dots comprises the following steps of: firstly, preparing an admium telluride quantum dot with excellent fluorescent characteristic by hydrolyzing a sulfhydryl group; secondly, adding thiourea with a certain concentration into the reacted admium telluride solution, forming free suplfur ions released by slowly hydrolyzing and photolyzing thiourea and cadmium ion dangling bonds existing on the surface of the admium telluride quantum dot into bonds; generating a thin cadmium sulfide casing layer on the surface of the cadmium sulfide quantum dot; and finally adding a zinc acetate solution and a sodium sulfide solution into the admium telluride/cadmium sulfide quantum dots with nuclear shell structures and carrying out hydro-thermal growth in a polytetrafluoroethylene digestion tank to form the admium telluride/cadmium sulfide/zinc sulfide quantum dots. The quantum dots have the characteristics of high fluorescent strength, favorable stability, high quantum yield and low biotoxicity and are hopeful to be applied to the field of biomarkers instead of the traditional organic dye. The synthetic method has the advantages of simple process, convenience, low cost and strong operability.
Owner:SHANGHAI UNIV

Recombinant Pseudomonas putida CH01 capable of adsorbing heavy metal cadmium and application thereof

The invention belongs to the soil environment management field in the environmental engineering and relates to the construction and application of a new genetically engineered microorganism capable of restoring the soil polluted by heavy metal cadmium. The preparation method of the genetically engineered microorganism comprises the following steps: monkey metallothionein alpha structure domain tetramer is fused in the ice-nucleating protein N-end of Xanthomona campestris ATCC33913 to be used as a main functional unit for constructing a broad host range expression plasmid; then cadmium-specific promoter is used for expression in Pseudomonas putida X4 which can resist various heavy metals efficiently, thus realizing the surface display of monkey metallothionein alpha structure domain tetramer in the bacterium and obtaining genetically engineered microorganism CH01 which can adsorb heavy metal cadmium efficiently and specifically. The engineered microorganism can remarkably adsorb heavy metal cadmium in the presence of various heavy metals; and the result of the symbiotic water culture with wheat, cowpea and corn shows that the engineered microorganism CH01 can colonize in the rhizosphere of plant and fast adsorb cadmium ions. The invention also discloses a construction method of the genetically engineered microorganism CH01 of which preservation number is CGMCC No.M209320.
Owner:HUAZHONG AGRI UNIV

Method for catalyzing ring-opening polymerization of cyclic ester by zinc catalyst

The invention discloses a method for catalyzing ring-opening polymerization of cyclic ester by a zinc catalyst, and belongs to the technical field of polymer synthetic materials. The problems that anexisting zinc catalyst for catalyzing ring opening of cyclic ester needs the participation of support ligands, and reaction activity and controllability are improved by changing steric hindrance and electrical property of central metal are solved. According to the invention, under the catalysis of a bis(hexaalkyldisilazane)zinc catalyst, lactone is initiated by an alcohol compound to carry out a ring-opening polymerization reaction, and a polyester material with rich structure is obtained. The catalyst adopted by the invention is a green and environment-friendly bis(hexaalkyldisilazane)zinc catalyst which does not need ligand participation, efficient and high-controllable active polymerization of different lactones can be realized under mild conditions, and the monomer universality is verygood, so that various polyester materials with different structures are obtained. The system has good universality for ring-opening polymerization of cyclic ester monomers, catalyzes the synthesis ofvarious degradable polyester materials, and promotes the development of sustainable polymers.
Owner:QINGDAO INST OF BIOENERGY & BIOPROCESS TECH CHINESE ACADEMY OF SCI

Method for preparing polyester by catalyzing cyclic anhydride/epoxide ring opening alternate copolymerization with potassium acetate

The invention relates to a method for preparing polyester by catalyzing cyclic anhydride/epoxide ring opening alternate copolymerization with potassium acetate. According to the method, potassium acetate catalyzes an epoxy compound and cyclic anhydride to be subjected to ring-opening alternate copolymerization to synthesize polyester, wherein potassium acetate is used as a catalyst to catalyze thecopolymerization of the cyclic anhydride and the epoxy compound, the reaction formula is defined in the specification, R1 and R2 are anhydride substituents, are the same or different, and simultaneously or independently are a hydrogen atom, a double bond, a benzene ring or a norbornene ring, and R3 and R4 are epoxy compound substituents, and are simultaneously or independently H, methyl, benzenering or cyclohexyl. The preparation method comprises the following steps: carrying out a polymerization reaction on excessive epoxide, cyclic anhydride and potassium acetate by using a normal-pressurebulk polymerization method, precipitating the polymer, filtering, and drying. Compared with the existing metal organic catalyst and non-metal organic catalyst, the potassium acetate provided by the invention has low biotoxicity, low price and simple preparation method, and has great application prospects.
Owner:TIANJIN UNIV

Treatment system and technology for fermented antibiotics wastewater

The invention discloses a treatment system for ferment antibiotics wastewater. The treatment system comprises an adjusting tank, a cavitation air floatation machine, a coagulative precipitation tank,a hydrolysis acidification tank, a UASB reactor, a primary sedimentation tank, an A/O system, a secondary sedimentation tank, a Fenton oxidation reaction box, a reaction sedimentation tank and a sludge thickening tank which are successively connected. The invention further discloses a treatment method for the ferment antibiotics wastewater. The treatment method comprises the following steps: pretreatment: the adjusting tank, the cavitation air floatation machine and the coagulative precipitation tank; biochemical treatment: the hydrolysis acidification tank, the UASB reactor, the primary sedimentation tank, the A/O system and the secondary sedimentation tank; and advanced treatment: the Fenton oxidation reaction box and the reaction sedimentation tank. The combined technology is used for treating the ferment antibiotics wastewater, the biotoxicity of the ferment antibiotics wastewater is reduced, and the biodegradability of the wastewater is improved, so that the wastewater is discharged after reaching a standard, the treatment technology is simple, and the operating cost is low.
Owner:HANGZHOU XINGYUAN FILTER TECH

Gadolinium doped zinc oxide nano particles and preparation method thereof

The invention relates to gadolinium doped zinc oxide nanoparticles and a preparation method thereof. The gadolinium doped zinc oxide nanoparticles are characterized in that the gadolinium doped zinc oxide nanoparticles are evenly dispersed nanoparticles with diameter of 2-6 nm; fluorescence spectrum shows that the nanoparticles have excitation wavelength of 320-360 nm and emission wavelength of 500-560 nm; the excitation wavelength and the emission wavelength show redshift with the increase of the doping amount of gadolinium; the fluorescence intensity first increases then decreases with the increase of the doping amount of gadolinium; and when a molar ratio of zinc to gadolinium is at 1:0.08, the fluorescence enhancement reaches the maximum. The product has application prospect in magnetic resonance and fluorescence double functional imaging. The invention has the advantages that a cheap zinc material with good biocompatibility is employed for direct synthesis of gadolinium doped zinc oxide nanoparticles through a sol-gel method, the method on the one hand reduces the toxicity of the final product, and on the other hand reduces the cost of the product, and the product has application prospect in magnetic resonance and fluorescence double functional imaging.
Owner:SHANGHAI NAT ENG RES CENT FORNANOTECH
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