Method for treating epilepsy by sublingual traditional Chinese medicine dropping pills containing cannabidiol

A technology of cannabidiol and sublingual administration, applied in the field of pharmacy, can solve the problems of slow effect, small prescription, and insignificant effect of traditional Chinese medicine preparations.

Pending Publication Date: 2022-08-02
深圳天成铭道医学科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to overcome the shortcomings of the single raw material of the existing Western medicine for the treatment of epilepsy, the effect of the traditional Chinese medicine preparation is not obvious and the effect is slow, etc., to provide a method for treating epilepsy with a sublingual Chinese medicine dripping pill containing cannabidiol. Dropping pills have small prescriptions and simple preparation methods, in which cannabidiol can help control the consumption of GABA neurotransmitters with a calming effect in the brain, effectively inhibit brain excitement, reduce seizures, and help improve the efficacy of other antiepileptic drugs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0010] The preparation of the traditional Chinese medicine dropping pills in the present invention is based on the parts by weight of the raw materials: it is composed of the following components: 20-30 parts of CBD (industrial hemp extraction), 20-30 parts of Tianma, 20-50 parts of Bupleurum, 5-10 parts of musk share

[0011] The preparation method includes the following steps:

[0012] Add the CBD extract to the medicine and add it into the melted polyethylene glycol 4000 and polyethylene glycol 6000 mixed matrix, stir well, put the medicine liquid in the storage tank of the pill dropping machine, keep warm (60 ℃), and drop into the cooling temperature of (0~4℃) liquid matrix, take it out, remove the condensate by dropping pills, and apply film coating. Water and different concentrations of alcohol are used for fat-soluble matrix dropping pills; paraffin and methyl silicone oil are used for water-soluble matrix dropping pills.

[0013] The method for taking the cannabidiol...

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Abstract

The invention discloses a method for treating epilepsy by sublingual traditional Chinese medicine dropping pills containing cannabidiol, belongs to the technical field of pharmacy, and particularly relates to a method for treating epilepsy by traditional Chinese medicine dropping pills containing cannabidiol. The method comprises the following steps: firstly, determining the combination and the components by weight of the traditional Chinese medicine dropping pill, independently extracting the industrial hemp raw material to obtain a cannabidiol (CBD) extract with higher purity, adding the CBD extract and a matrix into the medicine, suspending or melting, dripping, cooling, washing the pill, drying, selecting the pill, carrying out quality inspection, and subpackaging to form the dropping pill. Acute toxicity experiment evaluation is carried out on the traditional Chinese medicine dropping pill containing cannabidiol according to a new medicine approval method and a traditional Chinese medicine and natural medicine acute toxicity research technology guidance principle, the safety of the traditional Chinese medicine dropping pill is determined, and meanwhile actual case analysis shows that the traditional Chinese medicine dropping pill is remarkable in epilepsy treatment effect and wide in applicable crowd.

Description

technical field [0001] The invention belongs to the technical field of pharmacy, and in particular relates to a method for treating epilepsy with Chinese medicine dropping pills containing cannabidiol. Background technique [0002] Epilepsy is one of the most common diseases in neurology, and the World Health Organization (WHO) estimates that there are approximately 50 million epilepsy patients worldwide. In recent years, domestic epidemiological data show that the prevalence of epilepsy in my country is between 4‰ and 7‰. It is estimated that there are about 10 million epilepsy patients in my country, of which about 6 million are active epilepsy, and about 400,000 new cases are diagnosed every year. epilepsy patients. According to foreign statistics, about 70% of epilepsy patients can have their seizures completely controlled or significantly reduced after regular antiepileptic drug treatment, but still about 30% of epilepsy patients have uncontrollable symptoms and develop...

Claims

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Application Information

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IPC IPC(8): A61K36/8988A61K31/05A61K9/20A61P25/08A61K35/55
CPCA61K31/05A61K36/8988A61K36/233A61K35/55A61K9/006A61K9/2031A61P25/08A61K2300/00
Inventor 周禹州莫建红李勇胡宗辰
Owner 深圳天成铭道医学科技股份有限公司
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