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Traditional Chinese medicine oral liquid treating haemophilus parasuis disease and preparation method thereof

A technology of Haemophilus suis and traditional Chinese medicine oral liquid, which is applied in antibacterial drugs, medical formulas, medical preparations containing active ingredients, etc., can solve the problems of drug-resistant drug residues and achieve definite curative effect

Inactive Publication Date: 2015-03-04
GREAT BIOLOGY PHARMA TIANJIN
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the treatment of Haemophilus parasuis mainly relies on oral or injection antibiotics, which are prone to drug resistance and drug residues

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] A traditional Chinese medicine oral liquid for treating Haemophilus parasuis disease, the parts by weight of each raw material are as follows: 10 parts of aconitum, 20 parts of peony, 20 parts of astragalus, 10 parts of licorice, 15 parts of ephedra, 10 parts of Atractylodes macrocephala, and 10 parts of Fangfeng , 10 parts of aconite, 20 parts of Poria cocos, 10 parts of cassia twig. The preparation method is as follows: (1) crushing the traditional Chinese medicine to 80 meshes, weighing according to the formula amount, and three-dimensionally mixing the Chinese medicine powder; (2) putting the mixed Chinese medicine powder and 200 parts of water into an extraction tank and soaking for 8 hours; (3) Extract by heating to 100°C for 8 hours; (4) Filter and collect the medicinal solution; (5) Add 200 parts of water to the remaining medicinal residue, and extract at 100°C for 8 hours; (6) Remove medicinal residue by filtration, and combine two extractions liquid, concentra...

Embodiment 2

[0031] A traditional Chinese medicine oral liquid for treating Haemophilus parasuis disease, the parts by weight of each raw material are as follows: 5 parts of aconitum, 10 parts of peony, 20 parts of astragalus, 10 parts of licorice, 10 parts of ephedra, 20 parts of Atractylodes macrocephala, and 15 parts of Fangfeng , 15 parts of aconite, 20 parts of poria cocos, 10 parts of cassia twig. The preparation method is as follows: (1) crushing the traditional Chinese medicine to 80 meshes, weighing according to the formula amount, and three-dimensionally mixing to obtain the Chinese medicine powder; (2) putting 200 parts of the mixed Chinese medicine powder and water into an extraction tank and soaking for 8 hours; (3) Extract by heating to 100°C for 8 hours; (4) Filter and collect the medicinal solution; (5) Add 200 parts of water to the remaining medicinal residue, and extract at 100°C for 8 hours; (6) Remove medicinal residue by filtration, and combine two extractions liquid, ...

Embodiment 3

[0033] A traditional Chinese medicine oral liquid for treating Haemophilus parasuis, the parts by weight of each raw material are as follows: 10 parts of aconitum, 20 parts of peony, 15 parts of astragalus, 20 parts of licorice, 15 parts of ephedra, 10 parts of Atractylodes macrocephala, 10 parts of Fangfeng, 15 parts of aconite, 10 parts of poria cocos, 15 parts of cassia twig. The preparation method is as follows: (1) crushing the traditional Chinese medicine to 80 meshes, weighing according to the formula amount, and three-dimensionally mixing to obtain the Chinese medicine powder; (2) putting 200 parts of the mixed Chinese medicine powder and water into an extraction tank and soaking for 8 hours; (3) Extract by heating to 100°C for 8 hours; (4) Filter and collect the medicinal solution; (5) Add 200 parts of water to the remaining medicinal residue, and extract at 100°C for 8 hours; (6) Remove medicinal residue by filtration, and combine two extractions liquid, concentrated...

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PUM

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Abstract

The invention relates to a traditional Chinese medicine oral liquid treating haemophilus parasuis disease and a preparation method thereof. The traditional Chinese medicine oral liquid is prepared from radix aconiti kusnezoffii, white peony root, radix astragali, radix glycyrrhizae, herba ephedrae, rhizoma atractylodis macrocephalae, radix saposhnikoviae, prepared common monkshood daughter root, poria and ramulus cinnamomi. The traditional Chinese medicine composition can be an oral liquid, and is prepared according to the following steps: (1) crushing traditional Chinese medicines into 80-100 mesh, weighing according to a prescription, and performing three-dimensional mixing to obtain a traditional Chinese medicine powder; (2) adding the mixed traditional Chinese medicine powder and 100-200 parts by weight of water into an extraction tank and immersing for 5-20 h; (3) heating to 40-100 DEG C and extracting for 6-10 h; (4) filtering and merging the medicinal liquids; (5) continuing to add 100-200 parts by weight of water into the herb residue, and extracting at 40-100 DEG C for 6-10 h; (6) filtering to remove herb residue, merging the two times of extraction liquids, performing reduced-pressure concentration at 30-70 DEG C to have a volume being 20-40% of the original volume; and (7) loading bottles each with 250 mL, so as to obtain a finished product. The provided traditional Chinese medicine oral liquid is capable of effectively treating haemophilus parasuis disease with the cure rate of 95% or more. The composition has the effects of promote sweating to release the exterior and diffuse impediment, warming the meridian to dissipate cold, eliminating dampness and relieving pain, and inducing diuresis to alleviate edema.

Description

technical field [0001] The invention belongs to the field of Chinese veterinary medicine preparations, in particular to a traditional Chinese medicine oral liquid for treating Haemophilus parasuis disease and a preparation method thereof. Background technique [0002] Haemophilus parasuis disease: also known as multiple fibrinous serositis and arthritis. Can cause Graves' disease in pigs. Clinically, it is an infectious disease characterized by elevated body temperature, joint swelling, dyspnea, polyserositis, arthritis and high mortality, which seriously endangers the health of piglets and young pigs. At present, Haemophilus parasuis disease has affected the development of pig industry in the world and brought huge economic losses to the pig industry. Haemophilus parasuis only infects pigs, and can affect young pigs from 2 weeks to 4 months. It mainly occurs around weaning and in the nursery stage. It is usually seen in pigs aged 5 to 8 weeks, and the incidence rate is ge...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/714A61K9/08A61P31/04A61P19/02
CPCA61K36/714A61K9/08A61K36/076A61K36/17A61K36/238A61K36/284A61K36/481A61K36/484A61K36/54A61K36/65A61K36/71A61K2236/15A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 李琳曲荟芬黄健刘志辉
Owner GREAT BIOLOGY PHARMA TIANJIN
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