Method and system for diagnosing uterine contraction levels using image analysis

A uterine contraction and uterine technology, applied in image analysis, 2D image generation, diagnosis, etc., can solve problems such as inability to distinguish from contractions, movement of boundaries, and noise.

Inactive Publication Date: 2015-07-29
FERRING BV
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  • Summary
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  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

A disadvantage of the M-mode approach in detecting uterine contractions is that it does not provide a means of segmenting the entire uterus, only the upper and lower borders that exist within user-specified intersections
The absence of this provision becomes pronounced in the case of exacerbated bowel or respiratory movements that may change the position of the gap in the previously marked uterine border
Additionally, the uterus may move back and forth relative to the intersection that has been set
This shift may appear to be uncorrelated, but it may result in partial gra

Method used

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  • Method and system for diagnosing uterine contraction levels using image analysis
  • Method and system for diagnosing uterine contraction levels using image analysis
  • Method and system for diagnosing uterine contraction levels using image analysis

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Embodiment

[0080] In order to validate the computer-based deformable model network application method, a clinical study is presented to provide cross-validation of the method against intrauterine pressure measurements. The study involved patients undergoing controlled ovarian stimulation and volunteering for mock embryo transfer (mock ET) and intrauterine pressure assessment. All volunteers underwent controlled ovarian stimulation and had mock ET. Although initially, stimulation cycles in the included patients were designed as treatment cycles, in all cases further treatment was not possible due to exacerbated ovarian response or fertilization failure. After agreeing to the procedure, patients received standard progesterone support (200 mg tid of micronized progesterone, transvaginally). Mock ET and ultrasound scans were performed 2 days after oocyte collection or 2 days + 36 hours after hCG administration in persons who had not initiated oocyte collection. An evaluation in two menstru...

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Abstract

Method of analyzing uterine contractions by analyzing uterine images using deformable model networks in support of embryo transfer techniques. The method is also used to diagnose premature uterine contractile activity in mammals. The method can be used to control contractile activity during embryo transfer or premature labor when used in conjunction with oxytocin antagonists.

Description

Background technique [0001] Detection of uterine contraction activity is necessary in a variety of medical procedures, including embryo transfer during in vitro fertilization, and detection and prevention of preterm birth during pregnancy. [0002] Increased uterine contractility in women undergoing embryo transfer ("ET") may affect ET success rates. Successful implantation rates were up to 3 times higher in ET recipients with a "silent" uterus compared to patients with elevated uterine contractility. It is currently hypothesized that administration of oxytocin antagonists may reduce uterine contractions and may increase pregnancy rates. In transplantation studies conducted in mice, it was confirmed that oxytocin antagonists reversed the negative effects of oxytocin. [0003] In humans, ethical issues preclude the use of invasive techniques for the assessment of uterine contractions, such as intrauterine pressure measurement in patients about to undergo embryo transfer proce...

Claims

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Application Information

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IPC IPC(8): A61B8/08A61B5/00G06T7/00
CPCA61B8/08G06T2207/20116A61B8/485G06T2207/30004G06T7/0089A61B2576/00A61B5/4356A61B8/5223G06T2207/10132G06T7/0083G06T7/12G06T7/149A61P15/04G16H50/30A61B17/435A61B2576/02G06T11/206G06T2207/30044G06T2210/41
Inventor 彼得·彼任斯基瓦尔德马·库琴斯基
Owner FERRING BV
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