Method and system for carrying out individual identification and paternity testing on Chinese populations and individuals

A parent-child identification and individual technology, applied in biochemical equipment and methods, microbial determination/inspection, etc., can solve problems such as difficulty in application, and achieve good detection results and high accuracy.

Active Publication Date: 2016-03-30
INST OF FORENSIC SCI OF MIN OF PUBLIC SECURITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In this case, it is difficult to apply a STR fluore

Method used

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  • Method and system for carrying out individual identification and paternity testing on Chinese populations and individuals
  • Method and system for carrying out individual identification and paternity testing on Chinese populations and individuals
  • Method and system for carrying out individual identification and paternity testing on Chinese populations and individuals

Examples

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Embodiment 1

[0055] Embodiment 1, the accuracy of the system for individual identification and paternity identification of Chinese population individuals of the present invention

[0056] The system of the present invention includes a DNA extraction system, a composite detection system for STR loci, and an inference system;

[0057] The DNA extraction system is used to obtain the DNA of the individual to be detected;

[0058] The STR locus composite detection system is used to obtain the typing results of the DNA's 23 autosomal STR loci, the sex-determining locus Amelogenin, and the Y-STR locus DYS391;

[0059] The inference system is used for individual identification and paternity identification based on typing results,

[0060] 其中所述23个常染色体STR基因座为D1S1627、D3S4529、D2S441、D17S974、D6S1017、D4S2408、D9S2157、D17S1301、D1GATA113、D18S853、D20S482、D14S1434、D20S1082、D6S474、D12ATA63、D22S1045、D10S1248、D1S1677、D11S4463、D9S1122 , D2S1776, D5S2500 and D18S51.

[0061] The genotyping of 25 loci is carrie...

Embodiment 2

[0092] Based on the data obtained from the survey of 209 unrelated individuals in the Han population in northern China, the allele frequency, genotype frequency, observed heterozygosity, individual recognition ability, and polymorphism of the fluorescent marker STR multiple amplification test system in the Chinese Han population were calculated. Sexual information content and non-parent exclusion rate. The cumulative matching probability (PM) of all 23 non-CODIS system STR loci in the system constructed in this study is 8.4528×10 -22 , the cumulative individual discrimination power (TDP) was 0.99999999999999999999915472, and the cumulative non-parent exclusion probability (CEP) was 0.999999672. The STR loci are highly polymorphic in the Chinese Han population, and can be used for forensic individual identification and paternity identification.

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PUM

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Abstract

The invention provides a method and system for carrying out individual identification and paternity testing on Chinese populations and individuals. The method comprises: obtaining DNA of a to-be-tested individual; obtaining genotyping results of an autosomal STR locus, a sex determination locus Amelogenin and a Y-STR locus DYS391 of the DNA; and carrying out individual identification and paternity testing according to the genotyping results. The invention also provides the system for carrying out individual identification and paternity testing on Chinese populations and individuals. According to the scheme of the invention, by comprehensively analyzing the genotyping results of the autosomal locus and the sex determination locus, a genotyping result of the to-be-tested individual can be effectively obtained, and then a strong technical support is provided for public security organs to carry out individual identification and paternity testing.

Description

technical field [0001] The invention relates to a typing method and system, in particular to a method and system for individual identification and paternity identification of Chinese population individuals. Background technique [0002] With the increasing pace of my country's reform and opening up, people's traditional concept of family loyalty has also undergone subtle changes, making the relationship between modern families increasingly complicated. Divorce and remarriage happen around us almost every day. Extramarital affairs and other tests Incidents involving our moral bottom line have also increased significantly, and with it, the number of cases concerning parent-child relationship disputes accepted by courts across the country has continued to increase. With the increasing number of parent-child disputes and the continuous development and progress of DNA identification technology, parent-child identification based on DNA scientific identification technology has becom...

Claims

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Application Information

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IPC IPC(8): C12Q1/68
CPCC12Q1/6888C12Q2600/156
Inventor 白雪姚伊人赵兴春叶健王乐
Owner INST OF FORENSIC SCI OF MIN OF PUBLIC SECURITY
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