Application of nifedipine to preparation of medicine for preventing brain blood vessel injury caused by zero gravity

A nifedipine and cerebrovascular technology, which is applied in drug combinations, cardiovascular system diseases, medical preparations containing active ingredients, etc., can solve the problems that the weightlessness environment cannot be eliminated and the effect is limited, and the mechanism of action and toxic and side effects are clear , reduce time and cost, use safe effect
CN105582010AInactive Publication Date: 2016-05-18FOURTH MILITARY MEDICAL UNIVERSITY
0 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
FOURTH MILITARY MEDICAL UNIVERSITY
Publication Date
2016-05-18
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention discloses application of nifedipine to preparation of medicine for preventing brain blood vessel injury caused by zero gravity. The nifedipine can realize differential regulation and control on the function of brain and mesenteric small artery of simulated zero gravity rats through the inhibition effects on L type Ca<2+> channels, i.e., the nifedipine can recover the function of the brain artery blood vessels of the simulated zero gravity rats through inhibiting the L type Ca<2+> channels of smooth muscle cells of the brain artery blood vessels; and the nifedipine does not have the obvious influence on the function of the mesenteric small artery blood vessels and the L type Ca<2+> channels of smooth muscle cells of the simulated zero gravity rats.
Need to check novelty before this filing date? Find Prior Art

Description

Technical field

[0001] The invention belongs to the technical field of preventing and treating cerebrovascular remodeling caused by weightlessness and other environments, and relates to the application of nifedipine in preventing and treating cerebrovascular damage. Background technique

[0002] Aerospace activities are a special activity. When conducting aerospace activities, the human body is in a weightless / microgravity environment. In this case, the blood in the human body that has adapted to the 1G gravity of the earth's surface will shift headward and thus bring about A series of physiological and psychological problems have an impact on the physical health and work efficiency of astronauts. When the space flight activities are over and the astronauts return to the 1G gravity environment on the earth's surface, their cardiovascular functions will have obvious dysfunction. Phenomenon, such as poor orthostatic endurance and decreased exercise endurance. The incidence an...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More