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Honeysuckle dropping pills and preparation method thereof

A technology for extracting honeysuckle and honeysuckle, which is applied in pill delivery, pharmaceutical formulations, medical preparations of non-active ingredients, etc. It can solve the problems of less extraction, achieve the effects of accelerating the dissolution rate, reducing the particle size, and improving the absorption effect

Inactive Publication Date: 2016-05-25
SHENZHEN XIANKANGDA BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the components of honeysuckle extract are mainly a variety of chlorogenic acid compounds, and the extraction amount of medicinal ingredients such as volatile oil, flavonoids, triterpenoids and organic acids in honeysuckle is less

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0035] Prepare honeysuckle dripping pills, the following steps are as follows:

[0036] Step 1. Crush: Freeze the honeysuckle at minus 15°C for 50 minutes, and dehydrate and expand the frozen honeysuckle in a temperature-variable pressure-difference puffing equipment. The pressure of dehydration and puffing is 10-14kPa for 1-2 hours. Adding dry ice particles with a particle size of 35 μm to the dehydrated and expanded honeysuckle with a mass ratio of honeysuckle and dry ice particles of 3:1, and using a high-energy nano-impact mill to pulverize the mixed powder to 50 nm to obtain fine powder of honeysuckle; wherein, The mass ratio of ball material and honeysuckle powder in the high-energy nano impact mill is 6:1, and the ball material is berkelium dioxide;

[0037] Step 2. Extraction: the mass ratio of honeysuckle fine powder to absolute ethanol is 1-3:1, and the honeysuckle fine powder is loaded into supercritical CO 2 In the extraction tank of the extraction device, add abs...

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Abstract

The invention provides a preparation method of honeysuckle extract. The preparation method comprises the following steps: (I) freezing honeysuckle and dehydrating and puffing; (II) adding dry ice particles to form mixed powder particles, and pulverizing the mixed powder particles until the particle size is 30-75nm to obtain fine honeysuckle powder; (III) mixing the fine honeysuckle powder with absolute ethyl alcohol, and performing supercritical CO2 extraction; (IV) separating CO2 and volatilizing ethyl alcohol to obtain honeysuckle extract; and (V) preparing honeysuckle dropping pills. In the step (II), the mass ratio of the honeysuckle to the dry ice particles is (2-3.5):1. According to the extraction method of honeysuckle extract provided by the invention, active ingredients in honeysuckle are extracted to the greatest degree and made into dropping pills, thus the particle size of insoluble medicines can be remarkably reduced, the diffusion area is increased, the dissolution of medicinal components is facilitated, and the absorption effect is improved.

Description

technical field [0001] The invention belongs to the field of health food, in particular to a honeysuckle dripping pill and a preparation method thereof. Background technique [0002] Honeysuckle has been hailed as a good medicine for clearing heat and detoxification since ancient times. It can dispel wind-heat and clean blood toxins. It is used for various febrile diseases, such as body heat, rashes, spots, heat-toxin sores, sore throat, etc. evidence, the effect is significant. At present, the components of honeysuckle extract are mainly various chlorogenic acid compounds, and the extraction amount of medicinal components such as volatile oil, flavonoids, triterpenoids and organic acids in honeysuckle is relatively small. For these extracts, how to make them be absorbed and utilized by the human body is a difficult problem in the industry. Contents of the invention [0003] In order to solve the above-mentioned technical problems, the present invention provides a honeys...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61K47/10A61K36/355A61P17/00A61P11/04
CPCA61K9/2031A61K36/355A61K2236/37
Inventor 谢海涛周秋云谢来宾董玉峰陈佩王鹏亭柴行
Owner SHENZHEN XIANKANGDA BIOTECH CO LTD
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