Human brain local water distribution volume determining method taking cerebra gray matter as reference region

A determination method and technology for water distribution, applied in the field of biological and medical imaging, can solve problems such as insufficient accuracy, achieve good application scenarios, and facilitate automatic processing.

Active Publication Date: 2016-07-13
上海蓝生脑科医学研究有限公司
View PDF6 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] In order to solve the deficiencies in the prior art, the object of the present invention is to provide a method for measuring the local water distribution volume of the human brain

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Human brain local water distribution volume determining method taking cerebra gray matter as reference region
  • Human brain local water distribution volume determining method taking cerebra gray matter as reference region
  • Human brain local water distribution volume determining method taking cerebra gray matter as reference region

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0023] The present invention will be specifically introduced below in conjunction with the accompanying drawings and specific embodiments.

[0024] refer to figure 1 As shown, the method for measuring the local water distribution volume of the human brain with the gray matter of the brain as the reference area of ​​the present invention is a PET / H method of the local water distribution volume of the human brain. 2 15 O non-invasive quantitative measurement method, which can quantitatively measure the human brain pixel by pixel, and then generate functional images of the local water distribution volume of the human brain. In order to realize the above-mentioned purpose of the invention, the present invention is achieved by taking the following technical solutions:

[0025] The method for quantitatively measuring the volume of distribution of human brain local water as a reference area in the gray matter of the brain is characterized in that:

[0026] (1) PET / H for human brai...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a human brain local water distribution volume determining method taking cerebra gray matter as a reference region. The method is characterized by comprising the following steps that 1, PET/H2<15>O dynamic scanning is conducted on a human brain; 2, the cerebra gray matter of the human brain serves as the reference region, and a relative water distribution volume value P1 of each part to be calculated in the brain is calculated; 3, after the relative water distribution volume value P1 of each part of the human brain is calculated, normalization is conducted on the human brain according to needs; the obtained value only differs by a proportional constant from the absolute water distribution volume of the part, and the obtained value serves as an index of the absolute water distribution volume. According to the human brain local water distribution volume determining method taking the cerebra gray matter as the reference region, the arterial blood does not need to be dynamically drawn, a template or a model which is probably distorted is not needed, manual interventions such as complex modification are not needed, and therefore automated processing of a computer is achieved conveniently. Meanwhile, a deviation does not exist between the determined result and the result obtained through an accurate local water distribution volume quantitative determination method, and a good application prospect is achieved.

Description

technical field [0001] The invention relates to a method for measuring the local water distribution volume of the human brain, in particular to a method for measuring the local water distribution volume of the human brain using the gray matter of the brain as a reference area. The invention belongs to the field of biological and medical imaging. Background technique [0002] Using Positron Radionuclides 15 O labeled water (i.e. H 2 15 O) Positron Emission Tomography (PET) method (abbreviated as PET / H) as imaging agent 2 15 O method) is to carry out PET dynamic scanning after intravenous injection of H215O, and then use the Kety-Schmidt single-compartment model (for literature, see KetySS. (1951) The theory and application of the exchange of finert gas atthelungs and tissues. PharmacolRev3: 1-41.) and other methods for pixel-by-pixel quantification of local water distribution volume Compute, which produces an image of the local water distribution volume. [0003] In the...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61B6/00A61B5/107
CPCA61B5/1073A61B6/4057A61B6/481A61B6/501
Inventor 吴义根郑改革赵德林
Owner 上海蓝生脑科医学研究有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap