Calcipotriol composition with improved stability
A technology of calcipotriol and composition, applied in the field of compositions containing calcipotriol, capable of solving problems such as incomplete solution
Inactive Publication Date: 2017-01-04
JIANGSU SEMPOLL PHARMA
View PDF8 Cites 2 Cited by
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
[0007] The above-mentioned technology does not completely solve the above-mentioned problems, an
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View moreImage
Smart Image Click on the blue labels to locate them in the text.
Smart ImageViewing Examples
Examples
Experimental program
Comparison scheme
Effect test
Embodiment 1
[0033] The composition is as follows:
[0034]
[0035] Description: The neutralization degree of caprylic capric glyceryl arginine ester is 80%.
Embodiment 2
[0037] The composition is as follows:
[0038]
[0039] Description: The neutralization degree of caprylic capric glyceryl arginine ester is 0%.
Embodiment 3
[0041] The composition is as follows:
[0042]
[0043] Description: The neutralization degree of caprylic capric glyceryl arginine ester is 0%.
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more PUM
Login to view more Abstract
The invention discloses a calcipotriol composition with the improved stability. The composition is prepared from a vitamin D derivative or an analog (like calcipotriol), caprylic/capric glycerides arginine esterase and a pharmaceutically receivable additive. The stability of the composition is improved.
Description
technical field [0001] The present invention relates to a composition containing calcipotriol. More specifically, a calcipotriol-containing composition with improved stability. Background technique [0002] Calcipotriol ointment is mainly used for the treatment of stable plaque psoriasis suitable for topical treatment, and has become the drug of choice for the treatment of this disease. [0003] However, such topical pharmaceutical compositions containing vitamin D analogs suffer from stability problems. For example, calcipotriol is less stable at pH values below 8. Improvements have been made to a certain extent in the prior art for the above problems, for example: [0004] Patent CN00807667.7 discloses that the composition containing calcipotriol uses a solvent whose general formula is R(OCHC(R)H)xOR(I) as a stability protector, preferably polyoxypropylene-15-S-stearyl ether , Dovobet calcipotriol ointment, a product listed by Leo Pharmaceuticals, uses polyoxypropy...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more Application Information
Patent Timeline
Login to view more IPC IPC(8): A61K9/06A61K31/593A61K31/59A61K47/18A61P17/06A61P17/10A61P17/00
CPCA61K31/593A61K9/0014A61K9/06A61K31/59A61K47/18
Inventor 蔡蓓蕾王学政陈玉兰
Owner JIANGSU SEMPOLL PHARMA
Who we serve
- R&D Engineer
- R&D Manager
- IP Professional
Why Eureka
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Social media
Try Eureka
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap