Naoxueshu preparation method

Abstract

The invention discloses a Naoxueshu preparation method which comprises the following steps: (1) fetching acorus gramineus and cortex moutan, and extracting volatile oil; (2,3,4) fetching radix astragali, achyranthes bidentata, ligusticum wallichii and rheum officinale, grinding and merging with the residue; sequentially adding water with pH value of (1.5-2.5), (6.5-7.0) and (7.8-8.5); and heating and extracting; (5) fetching leech, adding normal saline and soaking; (6,7,8) sequentially adding water with pH value of (1.5-2.5), (6.5-7.0) and (7.8-8.5) into the filter residue, and heating and extracting; (9) merging the filtrate obtained in the steps (5,6,7,8), concentrating and drying to obtain hirudin; and (10) merging the filtrate obtained in the steps (2,3,4), and concentrating to obtain clear paste; adding the volatile oil and hirudin, and mixing uniformly; and adding pharmaceutically acceptable carrier or accessories to obtain a medicinal preparation. The Naoxueshu preparation obtained by the method has the advantages of high content of active ingredients, high bioavailability, better adaptability to human body absorption and the like.

Description

technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine naoxueshu preparation for treating apoplexy, belonging to the technical field of traditional Chinese medicine preparations. Background technique [0002] Cerebrovascular disease is one of the three major diseases that endanger human health in the world today. It is a frequently-occurring disease among middle-aged and elderly people with a high mortality rate. Cerebrovascular disease accounts for the second cause of death in my country. According to domestic reports, the mortality rate of cerebral hemorrhage is 38% to 43%, and about 50% to 70% of the survivors have severe sequelae and cannot take care of themselves. Not only the patients suffer great pain, but also bring burdens to families and society. [0003] Traditional Chinese medicine has its unique advantages in the treatment of cerebrovascular diseases. For example, the traditional Chinese medicine Naoxueshu Oral Liq...

AI Technical Summary

Problems solved by technology

[0004] Because the preparation process of the brain blood thinning preparation in the prior art is to extract the volatile oil of some medicinal materials, and the crude product of some medicinal materials is subjected to water extraction and alcohol precipitation, there are low content of active ingredients, large dosage, incomplete absorption, low bioavailability, etc. Inadequacies

With the continuous development of science and technology and the continuous improvement of the level of new drug research and development, the continuous application of new theories, new technologies, new processes, and new equipment, its traditional preparation process does not fully meet the requirements of modernization of traditional Chinese medicine.

Images