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Application of pyrroloquinoline quinine active matter in prevention and control of weaned piglet diarrhea

A technology of roloquinoline quinone and active substance, which is applied in the field of swine nutrition and reproduction, and can solve the problems of restricting the adequate intake of natural source nutrients by animals and the like

Pending Publication Date: 2017-02-01
CHANGMAO BIOCHEMICAL ENG CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The modern intensive large-scale feeding mode limits animals’ adequate intake of nutrients from natural sources to a certain extent

Method used

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  • Application of pyrroloquinoline quinine active matter in prevention and control of weaned piglet diarrhea
  • Application of pyrroloquinoline quinine active matter in prevention and control of weaned piglet diarrhea
  • Application of pyrroloquinoline quinine active matter in prevention and control of weaned piglet diarrhea

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] This example provides a specific application method of pyrroloquinoline quinone in the preparation of a composition for preventing and treating diarrhea in weaned piglets. Pyrroloquinoline quinone is added to the basal diet of weaned piglets in the form of an additive, and the growth status of weaned piglets is observed. The specific application steps are as follows:

[0027] 1. Experimental design and arrangement of experimental animals:

[0028] A total of 144 weaned piglets (Du×Long×Da) were selected for the experiment. The average weaning age was 28 days. The initial body weight of the experiment was 8.0±1.2kg. Each treatment has 6 repetitions, each repetition has 6 pigs, and the test period is 28 days.

[0029] 2. The preparation method of the cornstarch powder containing 1‰ of PQQ: mixing step by step. Specifically, mix PQQ and corn starch at a ratio of 1:9 to obtain a PQQ corn starch powder containing 10%, and mix 10% PQQ corn starch powder and corn starch at a...

Embodiment 2

[0065] This example provides a specific application of pyrroloquinoline quinone in preventing and treating diarrhea in weaned piglets. Pyrroloquinoline quinone is added to the basic diet of weaned piglets in the form of medicine or health care products, and the growth status of weaned piglets is observed. The specific application steps are as follows:

[0066] 1. Contains PQQ Na 2 Preparation and use of medicines or health products for preventing and treating diarrhea in weaned piglets

[0067] 1) Preparation:

[0068] ① Contains 1‰ of PQQ·Na 2 The preparation method of cornstarch powder: with embodiment 1.

[0069] ② Contains 1‰ of PQQ·Na 2 The preparation method of the glucose powder: mixing step by step. Specifically, the PQQ·Na 2 Mix with glucose at 1:9 to contain 10% PQQ Na 2 Glucose powder, 10% PQQ Na 2 Glucose powder and glucose are mixed at a ratio of 1:9 to obtain 1% PQQ Na 2 Glucose powder, 1% PQQ·Na 2 Glucose powder and glucose are mixed at a ratio of 1:9 ...

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Abstract

The invention provides application of pyrroloquinoline quinine active matter in prevention and control of weaned piglet diarrhea. It is found that by means of the pyrroloquinoline quinine active matter, the villus height of all sections of the small intestine of a piglet can be increased, the recess depth of the duodenum section and the jejunum section can be reduced, the expression quantity of jejunum mucosa tight junction ligandin ZO-1 and occludin can be increased, therefore, the diarrhea rate of the weaned piglet is remarkably reduced, and the feed conversion efficiency is improved. Therefore, pyrroloquinoline quinine has good application prospects in prevention, treatment and relief of generation and development of weaned piglet diarrhea.

Description

technical field [0001] The invention relates to the technical field of pig nutrition and reproduction in animal husbandry. More specifically, the present invention relates to the application of pyrroloquinoline quinone active substance in preventing and treating diarrhea of ​​weaned piglets. Background technique [0002] Although my country is a big pig raising country with an annual output of nearly 670 million pigs, there is still a big gap between the production level and the developed countries and regions in the world. This fact cannot be ignored. The modern intensive large-scale feeding mode limits animals' sufficient intake of natural source nutrients to a certain extent. With the gradual deepening of animal nutrition research, people continue to find the lack of nutrients in the current diet to supplement the needs of animals, aiming to meet the needs of animals and achieve the best production status. [0003] In the modern breeding process, the staged feeding of c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K50/30A23K50/60A23K20/137A23K10/30A23K10/37A23K10/22A23K10/28A23K20/20A23K20/24A23K20/22A61K31/437A61P1/12
CPCA61K31/437Y02P60/87
Inventor 王凤来尹鑫菂孙琳琳万屹东芮新生顾建新潘春
Owner CHANGMAO BIOCHEMICAL ENG CO LTD
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