High-fat high-sugar semi-liquid diet for inducing hyperlipidemia primate model and an inducing method thereof

Abstract

The invention discloses a high-fat high-sugar semi-liquid diet for inducing a hyperlipidemia primate model and an inducing method thereof. According to the high-fat high-sugar semi-liquid diet for inducing the hyperlipidemia primate model and the inducing method thereof, the amount of the intake high fat and high sugar of each animal every day can be quantized; moreover, the worry of animal intake amount insufficiency caused by taste change is avoided; high fat and high sugar can be taken timely and quantitatively, so that an inducing process of a hyperlipidemia model is greatly accelerated. The hyperlipidemia primate model manufactured by the invention has the advantages which cannot be unmatched by those of the hyperlipidemia model which is induced by a rodent, and can be applied to various types of lipid-reducing medicaments, particularly the research, development and evaluation of the biotechnological medicaments which are not suitable for a rodent model.

Description

[0001] Technical field: [0002] The invention belongs to the field of hyperlipidemia research, and in particular relates to a high-fat, high-sugar semi-liquid diet for inducing a primate model of hyperlipidemia and an induction method thereof. [0003] Background technique: [0004] With the progress of society and the improvement of material living standards, the dietary structure of human beings has undergone major changes, gradually transitioning from a vegetarian-based diet to a high-fat, high-sugar diet. Due to the improvement of material living standards and the large intake of high fat and high sugar, diseases have also increased significantly. The most common diseases are hyperlipidemia and atherosclerosis. Hyperlipidemia is divided into hypercholesterolemia, hypertriglyceridemia and mixed hyperlipidemia. Hyperlipidemia has no obvious clinical manifestations in the early stage, and its onset is hidden. When it is discovered, it often enters the next stage of the diseas...

AI Technical Summary

Problems solved by technology

The disadvantage of this method is that it does not take into account the living habits of primates who like to play with feed. During the feeding process, most of the feed is discarded by playing and wasted. Amount of sugar, not quantifiable

And because the feed contains high calories, and the taste of the feed itself has changed greatly, the animal will feel full after taking a certain amount of feed, and for self-protection, the animal will stop eating a larger amount of feed. Feed, resulting in a relatively reduced intake of high fat and high sugar, which greatly prolongs the modeling time

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