Medicine composition for preventing and treating pulmonary tuberculosis and preparation method thereof

A composition and tuberculosis technology, applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve problems such as insufficient penetration of chemical drugs, non-recovery of lesions, respiratory dysfunction, etc.

Inactive Publication Date: 2017-04-26
JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As we all know, low immunity is not only the main reason for the recurrence of pulmonary tuberculosis, but also the key to whether recurrent pulmonary tuberculosis can be cured; in addition, due to the poor blood circulation in the center of pulmonary tuberculosis lesions, chemical drugs cannot fully penetrate, so that the lesions cannot recover, resulting in lung cancer. Tissue damage, respiratory dysfunction, seriously affecting the patient's health and life

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Example 1: Pharmaceutical composition for preventing and treating tuberculosis and its preparation method

[0032] The composition and weight parts of the raw materials of the pharmaceutical composition for preventing and treating pulmonary tuberculosis: 345g sclerotinia sylvestris 315g big golden knife 126g echinacea 114g big fruit euonymus 107g;

[0033] Preparation:

[0034] (1) According to the ratio of the raw material medicine, take the sclerophyllum, sylvestris, big golden knife, purple tuber, and euonymus macrocarpa, mix them, use 18% ethanol as the solvent, and extract at 32℃. The extraction times are 12 times, each extraction time is 14 hours, and the solvent consumption is 47 times of the total weight of the API. After filtration, residue A and extract A are obtained. Extract A recovers ethanol and concentrates to a relative density of 1.02 , Filtered, the drug solution passes through the SP70 macroporous adsorption resin column, first eluted with water, and then e...

Embodiment 2

[0037] Example 2: Pharmaceutical composition for preventing and treating tuberculosis and its preparation method

[0038] The composition and weight of the raw materials of the pharmaceutical composition for preventing and treating pulmonary tuberculosis are as follows: 342g sclerophyllum sclerophyllum 318g scented radix 318g lavender knives 124g echinacea 116g euonymus macrocarpa 105g;

[0039] Preparation:

[0040] (1) According to the ratio of the raw material medicine, take the sclerophyllum, sylvestris, big golden knife, purple tuber, and euonymus macrocarpa, mix them, use 18% ethanol as the solvent, and extract at 32℃. The extraction times are 12 times, each extraction time is 14 hours, and the solvent consumption is 47 times of the total weight of the API. After filtration, residue A and extract A are obtained. Extract A recovers ethanol and concentrates to a relative density of 1.02 , Filtered, the drug solution passes through the SP70 macroporous adsorption resin column, fi...

Embodiment 3

[0043] Example 3: Pharmaceutical composition for preventing and treating tuberculosis and its preparation method

[0044] The composition and weight parts of the raw materials of the pharmaceutical composition for preventing and treating pulmonary tuberculosis are as follows: sclerophyllum 348g, sylvestris 312g, big gold knife 128g, echinacea 112g, big fruit euonymus 109g;

[0045] Preparation:

[0046] (1) According to the ratio of the raw material medicine, take the sclerophyllum, sylvestris, big golden knife, purple tuber, and euonymus macrocarpa, mix them, use 18% ethanol as the solvent, and extract at 32℃. The extraction times are 12 times, each extraction time is 14 hours, and the solvent consumption is 47 times of the total weight of the API. After filtration, residue A and extract A are obtained. Extract A recovers ethanol and concentrates to a relative density of 1.02 , Filtered, the drug solution passes through the SP70 macroporous adsorption resin column, first eluted wit...

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PUM

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Abstract

The invention discloses a medicine composition for preventing and treating pulmonary tuberculosis and a preparation method thereof. The medicine composition is proportionally prepared by taking colysis hemionitidea, scaevola pilosa, ovate neolepisorus herb, stenosolenium saxatiles and euonymus myrianthus as crude drugs. The medicine composition can be prepared into various dosage forms according to a conventional preparation process, and the curative effect for preventing and treating the pulmonary tuberculosis is obvious.

Description

Technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a pharmaceutical composition for preventing and treating tuberculosis and a preparation method thereof. Background technique [0002] For 50 years, chemotherapy has played a huge role in controlling the epidemic of tuberculosis, curing more than 90% of newly-treated tuberculosis patients. However, due to unreasonable combination medications, poor management, irregular medication and the increase in immune-damaged hosts, the proportion of drug-resistant patients in my country's tuberculosis patients is as high as 28% to 41%, and a large number of retreatment patients have appeared. Data shows that relapsed tuberculosis patients account for 15% to 20% of newly registered tuberculosis patients each year, making retreatment tuberculosis a major problem in tuberculosis control, and it is also the root cause of drug-resistant tuberculosis, especially multidru...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/37A61P11/00A61P31/06A61K36/185A61K36/12A61K36/30
CPCA61K36/185A61K36/12A61K36/30A61K36/37A61K2236/333A61K2236/39A61K2236/51A61K2236/55
Inventor 不公告发明人
Owner JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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