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Western medicine composition for treating fracture

A technology for treating fractures and a composition, applied in the field of western medicine, can solve problems such as the timeliness of the use of adverse drug reactions, and achieve the effects of good long-term effect, reduced apoptosis and lasting therapeutic effect

Inactive Publication Date: 2017-05-31
HENAN BALING ELECTRONICS TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, drugs represented by methylprednisolone (methylprednisolone, referred to as methylprednisolone) have achieved certain curative effects in clinical application, but the adverse reactions of drugs and the timeliness of use make people continue to seek effective drugs. medicine

Method used

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  • Western medicine composition for treating fracture
  • Western medicine composition for treating fracture
  • Western medicine composition for treating fracture

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] In the embodiment of the present invention, a western medicine composition for treating fractures is composed of dextromethorphan hydrobromide and azithromycin; wherein, the mass ratio of dextromethorphan hydrobromide and azithromycin is 0.17: 1.

Embodiment 2

[0018] In the embodiment of the present invention, a western medicine composition for treating fractures is composed of dextromethorphan hydrobromide and azithromycin; wherein, the mass ratio of dextromethorphan hydrobromide and azithromycin is 0.22: 1.

Embodiment 3

[0020] In the embodiment of the present invention, a western medicine composition for treating fractures is composed of dextromethorphan hydrobromide and azithromycin; wherein, the mass ratio of dextromethorphan hydrobromide and azithromycin is 0.18: 1.

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PUM

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Abstract

The invention discloses a western medicine composition for treating fracture. The western medicine composition is prepared from dextromethorphan hydrobromide and azithromycin; the mass ratio of the dextromethorphan hydrobromide to the azithromycin is (0.17-0.22):1; when the western medicine composition is used for treating fracture, the adult injected dose is 0.95 mg / kg to 1.00 mg / kg, and the medicine feeding time is 6 hours to 24 hours after fracture. Testing therapy of fracture molding animals discovers that by means of the western medicine composition, apoptosis of cells can be reduced, surviving of neuron is promoted, forming of glial scars is inhibited, the BBB scores of the animals after treatment are remarkably increased, and it shows that the western medicine composition has the remarkable promoting effect on movement function recovery after fracture. The western medicine composition is compared with current commonly-used medicine methylprednisolone for treating fracture in clinical, and the western medicine composition is wider in dose window, more lasting in treating effect and better in lasting effect.

Description

technical field [0001] The invention relates to the technical field of western medicine, in particular to a western medicine composition for treating fractures. Background technique [0002] With the development of the economic level of countries in the world, the incidence of fractures shows a trend of increasing year by year. Fracture refers to the corresponding changes of various motor, sensory and sphincter dysfunctions, abnormal muscle tone and pathological reflexes in the corresponding segments caused by external direct or indirect factors. Fractures are the most serious complication of spinal injuries, often leading to severe dysfunction of the limbs below the level of injury. Fractures will not only bring serious physical and psychological harm to patients themselves, but also cause a huge economic burden on the whole society. Due to the social and economic losses caused by fractures, the prevention, treatment and rehabilitation of fractures have become a major top...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/485A61K31/7052A61P19/08
CPCA61K31/485A61K31/7052
Inventor 不公告发明人
Owner HENAN BALING ELECTRONICS TECH CO LTD
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