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Cell extract and application thereof

A technology of extracts and cells, applied in the medical field, can solve the problems of primary photosensitive abnormalities, affecting the rods, etc., and achieve the effect of restoring vision and good biological safety

Inactive Publication Date: 2017-06-13
GUANGZHOU ZISHENG BIOLOGICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Over 190 genetic abnormalities can cause primary photosensitive abnormalities, some affecting rods first and then cones or vice versa

Method used

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  • Cell extract and application thereof
  • Cell extract and application thereof
  • Cell extract and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Example 1 Primary Efficacy Tests in Combination with Organ-Specific Cell Extracts

[0033] The main efficacy tests combined with organ-specific cell extracts were carried out in two cases, and we will present case overviews of both cases and the efficacy of the extracts described in this invention, where the results of the VEP Flash Test (VEP Flash Test) are as figure 2 As shown, the results of the ERG Photopic test (ERG light adaptation test) are as follows image 3 As shown, the results of ERG Scotopic test (ERG dark test) are as follows Figure 4 shown.

[0034] As we saw in the VEP test, there was a slight improvement in retinal function without a corresponding improvement in the retinocortical pathway.

[0035] Typical Case

[0036] A 15-year-old male patient with severe amblyopia since early childhood (manual right eye before injection, 6 / 60 visual acuity in the left eye), in addition to severe night blindness, color blindness and loss of reading ability.

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PUM

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Abstract

The invention discloses a cell extract. The cell extract comprises a low molecular weight peptide, wherein the low molecular weight peptide is provided by organ specific cells of animals; the organ specific cells are obtained from organs or tissues related with diseases; the peptide is a special peptide related with the visual path, so as to help a patient to restore the eyesight, color vision, view field and perception. The invention further discloses application of the extract in treating the retina degrading diseases, and the retina degrading diseases comprise retina degrading caused by retinitis pigmentosa, senile retinopathy, diabetic retinopathy, hypertensive retinopathy, retinopathy complication caused by autoimmune diseases, and poor optic nerve nutrients. The cell extract has the advantages that the bacteria and toxicity are avoided, the biological safety is better, and the patient is helped to restore the eyesight, color vision, view field and perception.

Description

technical field [0001] The invention relates to a cell extract and its use, belonging to the field of medicine. Background technique [0002] The retina is one of the most sensitive organs in our body and is affected by most chronic diseases such as diabetes, hypertension, dyslipidemia, autoimmune diseases (SLE, sclerosis, amyloidosis), chronic infectious diseases (TB- meningitis), and various genetic defects and genetic diseases. [0003] Epidemiological surveys show some figures on the prevalence of retinal degenerative diseases from three different categories of patients, as an example of a problem of real depth. The first category is genetic malformations affecting the retina. Retinitis pigmentosa and associated rod-cone and cone-rod dystrophies represent the majority of conditions that cause vision loss as well as blindness. The term retinitis pigmentosa represents a spectrum of adverse reactions to a large class of genetic disorders. More than 190 genetic abnormali...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/12A61K38/02A61P9/10A61P3/10A61P9/12A61P25/00
Inventor 阿拉阿贝德卡里姆穆罕默德福阿德
Owner GUANGZHOU ZISHENG BIOLOGICAL TECH CO LTD
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