1results about How to "Restore vision" patented technology

The present application provides use of NeuroD1 in preparation of a drug for converting retinal Muller glial cells into neurons. The present application also provides a method for converting mouse retinal Muller glial cells into neurons, which comprises overexpressing neurotranscription factor NeuroD1 in mouse retinal Muller glial cells. After overexpression of NeuroD1 in mouse retinas by using an adeno-associated virus vector, the present application induces conversion of retinal Muller glial cells into retinal neurons, which can be applied to repair retinas damaged or degenerated due to diseases, thereby restoring vision.