Rectal suppository LED (Light Emitting Diode) light source for photodynamic therapy of rectal cancers

A rectal plug and light source technology, applied in the field of photodynamic therapy of rectal cancer and micro-miniature LED rectal plug light source, can solve the problems of lack of light source and difficulties in clinical treatment, and achieve the effect of wide luminous area
CN106902468AActive Publication Date: 2017-06-30INST OF BIOMEDICAL ENG CHINESE ACAD OF MEDICAL SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
INST OF BIOMEDICAL ENG CHINESE ACAD OF MEDICAL SCI
Publication Date
2017-06-30

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Abstract

The invention discloses a rectal suppository irradiation light source for photodynamic therapy of rectal cancers, and belongs to a device for photodynamic therapy. A 635nm LED (Light Emitting Diode) light source, a lithium battery, a constant current control circuit and relevant circuits are packaged in a bullet-type rectal suppository having the length of about 3cm, the diameter of about 1cm and the front end slightly acute, wherein the packaging material is transparent epoxy resin adhesive. By such design, the overall light source can be placed in the rectum of a patient for photodynamic therapy, and is suitable for long-time and low-energy continuous irradiation. The photodynamic therapy process of rectal cancers is simplified, the compliance of patients is improved, the labor intensity of medical staffs is relieved, the cost of photodynamic therapy is reduced, the limitation of the photodynamic therapy space is broken, and patients can accept the therapy in clinics or at home. The light source involves in a scientific research experiment method as clinical reference data of rectal cancers.
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Description

technical field

[0001] The invention belongs to the field of light source design in photodynamic therapy research, and relates to a miniature LED rectal suppository light source that can be implanted in the rectum to realize long-term low-dose photodynamic therapy of rectal cancer. Background technique

[0002] Photodynamic therapy (PDT) is the use of specific wavelengths of light to excite photosensitizers to undergo photodynamic reactions, that is, a series of photochemical reactions, and the reaction products (excited singlet oxygen molecules) have strong oxidation properties and can kill A new technology to treat the cells of surrounding lesions and achieve the purpose of treatment.

[0003] The three elements of photodynamic therapy are photosensitizer, oxygen and light source. Traditional photodynamic therapy (acute photodynamic therapy, aPDT) irradiates the tumor with a relatively high-energy (50-500mW) laser for a short time (within 30 minutes) to stimulate the phot...

Claims

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