Tranquilizing and excitement allaying medicine based on enflurane
A technology for sedation, tranquility and enflurane, applied in the field of medicine, can solve problems such as malaise, sudden death, prolonging the time of apnea, etc., and achieve the effects of avoiding pain, fast subsidence, and fast hypnosis.
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[0024] The present invention will be further described in detail below in conjunction with test examples and specific embodiments.
[0025] Enflurane, chemical name: 2-chloro-1,1,2-trifluoroethyl difluoromethyl ether.
[0026] Structural formula:
[0027]
[0028] Divided formula: C3H2ClF5O
[0029] Molecular weight: 184.49
[0030] Physical and chemical properties: colorless volatile liquid, inhaled anesthetic; non-flammable and non-explosive, boiling point at standard atmospheric pressure is 59.9°C; vapor pressure at 25°C is 272mmHg; blood / air distribution coefficient is 1.8, brain / blood distribution coefficient is 1.45, The oil / gas distribution coefficient is 98.5; the MAC value is 1.68%.
[0031] Pharmacological characteristics: Enflurane enters the blood circulation through the respiratory tract through alveolar gas exchange, and finally reaches the brain to play its role by binding to the corresponding receptors of brain nerve cells. Enflurane inhibits the functio...
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