Sevoflurane based tranquilizer

A technology of calming the nerves and sevoflurane, applied in the field of medicine, can solve problems such as malaise, sudden death, prolonging the time of apnea, etc., and achieve the effects of avoiding pain, fast fading, and fast hypnosis

Inactive Publication Date: 2017-12-01
SICHUAN CANCER HOSPITAL
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, insomnia and anxiety are usually relieved by oral stable drugs on the market, but stable drugs have a time lag, which will cause drowsiness, fatigue, listlessness, etc. during the day; more seriously, suffer from sleep disorders. For insomniacs with apnea, because sleeping pills can prolong the time of apnea, sudden death may occur; at the same time, some patients are not suitable for taking oral tranquilizers or injecting tranquilizers

Method used

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  • Sevoflurane based tranquilizer
  • Sevoflurane based tranquilizer
  • Sevoflurane based tranquilizer

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Embodiment Construction

[0024] The present invention will be further described in detail below in conjunction with test examples and specific embodiments.

[0025] Sevoflurane, chemical name: fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether.

[0026] Structural formula:

[0027]

[0028] Molecular formula: C4H3F7O

[0029] Molecular weight: 200.05

[0030] Physical and chemical properties: Halogenated inhalation general anesthetic, non-flammable, explosive, colorless and clear, volatile liquid. Sevoflurane is aromatic and non-irritating. The boiling point at 760mmHg is 58.6°C.

[0031] The specific gravity at 20°C is 1.25. Vapor pressure: 157mm Hg at 20°C, 197mm Hg at 25°C, and 317mm Hg at 36°C.

[0032] Partition coefficient at 37°C: blood / air partition coefficient 0.63-0.69, water / air partition coefficient 0.36, olive oil / air partition coefficient 47-54, brain / air partition coefficient 1.15.

[0033] Sevoflurane is a colorless transparent liquid without additives or chemical st...

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Abstract

The invention relates to a sevoflurane based tranquilizer which comprises a drug and a drug carrier. The drug refers to sevoflurane. The drug carrier comprises a water absorbing material and a casing; the water absorbing material is used for carrying sevoflurane and the casing is used for covering the water absorbing material for preventing sevoflurane from volatilizing; the casing is provided with a slit, the slit is provided with a sealing unit, and sevoflurane volatilizes from the slit during treatment with the tranquilizer. The sevoflurane based tranquilizer is an inhaled drug for people to take in a breathing way, has quick action for reducing stress or tension, has low side effect, is extincted rapidly after taking effect, and has no influence on daily life and work of people taking the tranquilizer. Besides, the sevoflurane based tranquilizer is free of pungent smel and avoids tracheospasm or bronchospasm, and can be applied to sleeping induction for children.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a sevoflurane-based sedative and tranquilizer. Background technique [0002] With the gradual acceleration of the pace of life, the number of people who are often troubled by insomnia and anxiety is gradually increasing. At present, insomnia and anxiety are usually relieved by oral stable drugs on the market, but stable drugs have a time lag, which will cause drowsiness, fatigue, listlessness, etc. during the day; For insomniacs with apnea, because sleeping pills can prolong the time of apnea, sudden death may occur; at the same time, there is a problem that some patients are not suitable for oral tranquilizers or injection tranquilizers. Contents of the invention [0003] The purpose of the present invention is to provide a sevoflurane-based sedative and tranquilizer, which can improve some disadvantages of current tranquilizers in relieving insomnia, anxiety, irritability and other m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/08A61K9/72A61P25/20
CPCA61K31/08A61K9/0043
Inventor 唐育民刘寅张可贤周黎明张宏伟
Owner SICHUAN CANCER HOSPITAL
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