Nude mouse experimental device for non-contact thermal therapy research

Abstract

The invention discloses a nude mouse experimental device for non-contact thermal therapy research. The experimental device comprises a tubular container which is provided with an interlayer and a screw-in cover cap which is arranged at one end of the tubular container and is provided with a small hole, wherein one end of the tubular container provided with the interlayer is a conical end, and theother end of the tubular container is provided with an opening and inner screw threads are arranged on the inner wall of a port of the end, the interlayer is defined by the inner layer wall and the outer layer wall of the tubular container provided with the interlayer; the inner layer wall and the outer layer wall are connected by virtue of a connecting plate; air vents, which are not aligned, andspare slots, which are mutually aligned, are arranged in the inner layer wall and the outer layer wall of the tubular container provided with the interlayer; and the small hole is kept in the screw-in cover cap. Outer screw threads are arranged on the screw-in cover cap, and the outer screw threads are matched with the inner screw threads on the inner wall of the tubular container. The experimental device provided by the invention is simple in structure and diverse in functions; and by arranging the interlayer, an experimental animal is kept within an effective range of thermal therapy and isprotected from getting scalded due to direct contact with a heat source, and in addition, a penetrating effect of the thermal therapy on the human body can be simulated.

Description

technical field [0001] The invention mainly relates to the field of medical experimental equipment, in particular to a nude mouse experimental device for non-contact hyperthermia research. Background technique [0002] Hyperthermia is an important method in physical therapy. It uses various heat sources as mediators to transfer heat to the body to achieve therapeutic purposes. Studies have shown that after hyperthermia is combined with drugs, radiotherapy, and chemotherapy, the therapeutic effect will be better in tumor treatment, and the side effects will be reduced. At the same time, hyperthermia can also activate the immune system and improve the body's immunity. Systemic side effects are minimal. With the continuous in-depth research on the mechanism of hyperthermia treatment of diseases and the many advantages of hyperthermia itself, the treatment method of hyperthermia has also attracted more and more attention. [0003] Hyperthermia is divided into contact hyperther...

AI Technical Summary

Problems solved by technology

[0004] Nude mice are a commonly used experimental animal model and are widely used in basic research related to tumors and other diseases. However, in the current experimental research, there are few devices that combine non-contact hyperthermia with animal experiments. At the same time, due to the particularity of the nude mouse experimental animal model itself (such as nude mice are naturally active, the body surface has no hair covering, etc.), the device equipment needs to ensure that the nude mice can perform normal physiological activities during the hyperthermia process. Environment (certain activity space, constant and appropriate temperature, etc.), and nude mice need to be protected from bad injuries such as burns, and experimental devices that meet the above requirements have not been reported

Images