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Traditional Chinese medicine compound composition for treating venous thrombus as well as preparation and application thereof

A technology of venous thrombosis and composition, which is applied in the field of traditional Chinese medicine compound composition for the treatment of venous thrombosis, to achieve the effect of strong anti-platelet aggregation, simple manufacturing process, and reduction of thrombus formation

Inactive Publication Date: 2018-05-04
FIRST PEOPLES HOSPITAL OF YUNNAN PROVINCE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It is also the main reason why a powerful and effective thrombolytic traditional Chinese medicine has not yet been developed in China.

Method used

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  • Traditional Chinese medicine compound composition for treating venous thrombus as well as preparation and application thereof
  • Traditional Chinese medicine compound composition for treating venous thrombus as well as preparation and application thereof
  • Traditional Chinese medicine compound composition for treating venous thrombus as well as preparation and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] A preparation method of a Chinese medicine compound composition for treating venous thrombosis, comprising the steps of:

[0021] (1) 3 parts of Earthworm, 3 parts of Radix Notoginseng and 2 parts of Fructus Radix were extracted with 70% ethanol under reflux for 1 hour, and the extract and dregs were separated;

[0022] (2) Take the dregs in (1), 3 parts of Eupatorium, 3 parts of Hang Shao, 40 parts of dried ginger, 10 parts of cinnamon, 30 parts of ginseng, 15 parts of angelica, 5 parts of epimedium, and 10 parts of Morinda officinalis Extract with water, separate the extract and dregs;

[0023] (3) The extract obtained by combining (1) and (2) is concentrated to a thick extract.

Embodiment 2

[0025] A preparation method of a Chinese medicine compound composition for treating venous thrombosis, comprising the steps of:

[0026] (1) 30 parts of Earthworm, 30 parts of Panax notoginseng, and 30 parts of Fructus Rhododendron were extracted with 70% ethanol under reflux for 1 hour, and the extract and dregs were separated;

[0027] (2) Take the dregs in (1), 50 parts of Eupatorium, 60 parts of Hang Shao, 60 parts of dried ginger, 30 parts of cinnamon, 65 parts of ginseng, 35 parts of angelica, 40 parts of epimedium, and 45 parts of Morinda officinalis Extract with water, separate the extract and dregs;

[0028] (3) The extract obtained by combining (1) and (2) is concentrated to a thick extract.

Embodiment 3

[0030] A preparation method of a Chinese medicine compound composition for treating venous thrombosis, comprising the steps of:

[0031] (1) 20 parts of Earthworm, 15 parts of Panax notoginseng, and 10 parts of Fructus Radix L. were extracted with 70% ethanol under reflux for 1 hour, and the extract and dregs were separated;

[0032] (2) Take the dregs in (1), 20 parts of Eupatorium, 30 parts of Hang Shao, 50 parts of dried ginger, 20 parts of cinnamon, 45 parts of ginseng, 25 parts of angelica, 30 parts of epimedium, and 35 parts of Morinda officinalis Extract with water, separate the extract and dregs;

[0033] (3) The extract obtained by combining (1) and (2) is concentrated to a thick extract.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine compound composition for treating venous thrombus as well as preparation and application thereof. The traditional Chinese medicine compound composition is prepared from the following ingredients in parts by mass: 3 to 30 parts of earthworm, 3 to 30 parts of radix notoginseng, 3 to 50 parts of herba lycopi, 2 to 30 parts of fructus cinnamoii, 3to 60 parts of white paeony roots, 40 to 60 parts of rhizoma zingiberis, 10 to 30 parts of cortex cinnamomi, 30 to 65 parts of radix ginseng, 15 to 35 parts of radix angelicae sinensis, 5 to 40 partsof herba epimedii and 10 to 45 parts of radix morindae officinalis. During the preparation, the method comprises the following steps of (1) performing reflux extraction on the radix notoginseng, thefructus cinnamoii and the earthworm by 70-percent ethanol; separating extraction liquid and medicine slag; (2) extracting the medicine slag in the step (1), the herba lycopi, the white paeony roots, the rhizoma zingiberis, the cortex cinnamomi, the radix ginseng, the radix angelicae sinensis, the herba epimedii and the radix morindae officinalis by water; separating the extraction liquid and the medicine slag; (3) merging extraction liquid obtained in the step (1) and the step (2); performing concentration to obtain thick extracts. Compared with the prior art, the traditional Chinese medicinecompound composition provided by the invention has the advantages that the recipe is simple; the preparation process is simple and convenient; the obvious effect is achieved on the treatment of the venous thrombus.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a traditional Chinese medicine compound composition for treating venous thrombosis and its preparation and application. Background technique [0002] Thrombotic disease is a type of disease that seriously endangers human health and life, and its morbidity, disability and mortality are high. Clinically common thrombotic diseases include acute coronary syndrome, acute ischemic cerebrovascular disease , thrombosis in diabetic patients, thromboangiitis obliterans, thrombosis caused by acute tumors, etc. Thrombosis is a common and frequently-occurring disease that seriously endangers human health. Thrombosis and infarction play the most important role in myocardial infarction, cerebral infarction and pulmonary infarction. There are about 13 million cardiovascular deaths worldwide each year. In my country, the mortality rate of heart disease and cerebral apoplexy accounts for about ...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P7/02A61K35/62
CPCA61K35/62A61K36/232A61K36/258A61K36/296A61K36/53A61K36/54A61K36/65A61K36/71A61K36/746A61K36/9068A61K2236/331A61K2236/333A61K2236/39A61K2300/00
Inventor 杨国华李立纪苏勉诚陈志松赵仁彬沈晓梅
Owner FIRST PEOPLES HOSPITAL OF YUNNAN PROVINCE
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