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Glycated hemoglobin detection kit

A technology of glycosylated hemoglobin and detection kit, which is applied in the field of glycosylated hemoglobin detection, and can solve problems such as delayed disease, reduced test results, and reduced immune complexes

Active Publication Date: 2018-05-04
SICHUAN MACCURA BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] When the amount of hemoglobin can meet the amount of latex adsorption, the test results will not be affected, but when the amount of hemoglobin is reduced (such as anemia), the latex cannot reach the saturated adsorption amount, and the glycosylated hemoglobin antibody will be adsorbed on the latex, which is not conducive to Antigen-Antibody Specific Reaction
The immune complexes that lead to the formation of glycosylated hemoglobin antibodies are reduced, so that the test results are lowered, even lower than the lower limit of the reference range, which may mislead doctors to make wrong judgments and delay the treatment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0142] Embodiment 1: the preparation of glycosylated hemoglobin detection kit

[0143] All components shown in Table 1 below were mixed at the concentrations shown below to prepare Reagent R1 and Reagent R2.

[0144] Table 1

[0145]

Embodiment 2

[0146] Embodiment 2: the preparation of glycosylated hemoglobin detection kit

[0147] All components shown in Table 2 below were mixed at the concentrations shown below to prepare Reagent R1 and Reagent R2.

[0148] Table 2

[0149]

[0150]

Embodiment 3

[0151] Embodiment 3: the preparation of glycosylated hemoglobin detection kit

[0152] All components shown in Table 3 below were mixed at the concentrations shown below to prepare Reagent R1 and Reagent R2.

[0153] table 3

[0154]

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Abstract

The invention relates to the biotechnology field, in particular to a glycated hemoglobin detection kit. The glycated hemoglobin detection kit comprises a reagent R1 and a reagent R2, wherein the reagent R1 is prepared from rubber latex, a buffer solution A and a surfactant; and the reagent R2 is prepared from an anti-body, a buffer solution B and the surfactant. The kit can eliminate influences ofindividual hemoglobin content difference in glycated hemoglobin detection, is good in stability, and is convenient to use and store.

Description

technical field [0001] The invention belongs to the technical field of detection of glycosylated hemoglobin, in particular to a detection kit for glycosylated hemoglobin. Background technique [0002] Glycosylated hemoglobin (HbA1c) is the product of the combination of hemoglobin and blood sugar in red blood cells in human blood. The combination of blood sugar and hemoglobin to form glycosylated hemoglobin is an irreversible reaction, which is proportional to the blood sugar concentration and lasts for about 120 days, so the blood sugar concentration before 120 days can be observed. The glycosylated hemoglobin test can usually reflect the patient's blood sugar control in the past 8 to 12 weeks. [0003] The characteristics of glycosylated hemoglobin determine that it has great significance in diabetes monitoring: (1) It is parallel to the blood sugar value. The higher the blood sugar, the higher the glycosylated hemoglobin, so it can reflect the level of blood sugar contro...

Claims

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Application Information

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IPC IPC(8): G01N33/72
CPCG01N33/723
Inventor 甘萍萍耿英利黎明吴昌英龙腾镶
Owner SICHUAN MACCURA BIOTECH CO LTD
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