Absorbable gelatin hemostatic powder and preparation method thereof

A technology of hemostatic powder and gelatin, which is applied in the fields of medical formula, surgery, drug delivery, etc. It can solve the problems of product safety impact, tissue irritation and carcinogenicity, etc., and achieve good hemostasis, avoid irritation, and simple process.
CN108187129BActive Publication Date: 2021-08-31MEDPRIN REGENERATIVE MEDICAL TECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
MEDPRIN REGENERATIVE MEDICAL TECH
Publication Date
2021-08-31

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Abstract

The invention provides an absorbable gelatin hemostatic powder and a preparation method thereof, wherein the BET specific surface area of ​​the gelatin hemostatic powder is 30m 2 / g~70m 2 / g, and its preparation process includes the steps of cross-linking gelatin, water-absorbing swelling, mechanical pulverization, freeze-drying and secondary pulverization. The hemostatic powder can be well attached to the wound surface, quickly absorb the water in the blood, and achieve good hemostasis effect. Moreover, the preparation method has a simple process, further by adopting a cross-linking agent that does not participate in the reaction, and performing mechanical pulverization, ultrasonic-centrifugal cycle cleaning or ethanol aqueous cleaning operation after the gelatin is cross-linked and fully swollen, the cross-linking agent is effectively removed, The cross-linking agent has no residue in the hemostatic powder, avoids the irritating effect of the cross-linking agent on organisms, improves the safety of the product, and has good promotion and application value.
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Description

technical field

[0001] The invention relates to the technical field of hemostatic materials, in particular to an absorbable gelatin hemostatic powder and a preparation method thereof. Background technique

[0002] Surgical hemostasis is one of the important steps in clinical operations. Good hemostasis techniques and materials are the key to ensure the success of the operation. At present, commonly used hemostatic materials include hemostatic sponge, hemostatic gauze, hemostatic gel, hemostatic powder, etc. Among them, the hemostatic powder is not affected by the size and location of the wound, and can be used not only for surgical wounds, but also for microscopic wounds such as endoscopes. Invasive surgery has unique advantages.

[0003] In the prior art, the powdery hemostatic material is mainly a microporous polysaccharide product made of starch, and the polysaccharides on the surface of the starch granules are realized by ultrasonic method, wet heat treatment, microwave...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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