Magnetic test paper for detecting nitrite based on SERS and its preparation and use method

Abstract

The invention relates to SERS-based magnetic test paper for detecting nitrite as well as a preparation method and a use method thereof. The magnetic test paper comprises a super-hydrophobic film, goldnanorods and a magnetic composite, wherein the gold nanorods are erected on the surface of the super-hydrophobic film in bundles after self-assembling; the magnetic composite is entrained among the gold nanorods. The gold nanorods and the magnetic composite are self-assembled on the surface of the super-hydrophobic material to form the magnetic test paper with excellent SERS property. 4-amino thiophenol adsorbed on the surface of the magnetic test paper is coupled with to-be-detected nitrite, and an SERS signal of a coupling product is utilized, so that quantitative and qualitative detectionon the nitrite is conducted indirectly. The magnetic test paper prepared by the method is corrosion-resistant and staining-resistant, has excellent SERS property and magnetism, is convenient to carry,can be rapidly separated out of a complex system under the action of an external magnet, and has wide application prospect in on-site, rapid and high-sensitivity detection on the nitrite in complex samples such as food, environments and biological samples.

Description

Technical field

[0001] The invention relates to the technical field of nitrite detection, in particular to a SERS-based magnetic test paper for detecting nitrite and a preparation and use method thereof. Background technique

[0002] Nitrite is an intermediate product of the nitrogen cycle. It is unstable and can be seen everywhere in the natural environment. It is widely used in industry, construction and food processing industries. Studies have pointed out that nitrite is toxic, carcinogenic and teratogenic, and excessive consumption can be fatal. Nitrite itself is not carcinogenic, but it can react with various amino compounds under cooking or other conditions to be converted into nitrosamines, which is a carcinogen. After nitrite enters the blood, it combines with the hemoglobin in the human body, deforming the normal hemoglobin and losing its oxygen-carrying capacity, leading to hypoxia in human tissues and also having a dilation effect on blood vessels.

[0003] Nitrite is ...

Examples

Embodiment Construction

[0023] The present invention will be further explained below in conjunction with the drawings:

[0024] Such as Figure 1-Figure 3 A SERS-based magnetic test paper for detecting nitrite is shown, which includes a superhydrophobic film, a bunch of gold nanorods erected on the surface of the superhydrophobic film after self-assembly, and a magnetic composite sandwiched between the gold nanorods. SERS is the English abbreviation of Surface-enhanced Raman scattering, and the Chinese meaning is surface-enhanced Raman scattering. In the magnetic test paper of the present invention, the gold nanorods are vertically arranged on the surface of the superhydrophobic film and self-assembled into an array, and the top of the gold nanorods will have the greatest electromagnetic enhancement, so that the magnetic test paper has excellent SERS enhancement performance . On the surface of the superhydrophobic film, the magnetic compound (Fe 3 O 4 / TiO 2 / Au NRs) are surrounded by a gold nanorod a...

Technical field

[0001] The invention relates to the technical field of nitrite detection, in particular to a SERS-based magnetic test paper for detecting nitrite and a preparation and use method thereof. Background technique

[0002] Nitrite is an intermediate product of the nitrogen cycle. It is unstable and can be seen everywhere in the natural environment. It is widely used in industry, construction and food processing industries. Studies have pointed out that nitrite is toxic, carcinogenic and teratogenic, and excessive consumption can be fatal. Nitrite itself is not carcinogenic, but it can react with various amino compounds under cooking or other conditions to be converted into nitrosamines, which is a carcinogen. After nitrite enters the blood, it combines with the hemoglobin in the human body, deforming the normal hemoglobin and losing its oxygen-carrying capacity, leading to hypoxia in human tissues and also having a dilation effect on blood vessels.

[0003] Nitrite is ...

Examples

Embodiment Construction

[0023] The present invention will be further explained below in conjunction with the drawings:

[0024] Such as Figure 1-Figure 3 A SERS-based magnetic test paper for detecting nitrite is shown, which includes a superhydrophobic film, a bunch of gold nanorods erected on the surface of the superhydrophobic film after self-assembly, and a magnetic composite sandwiched between the gold nanorods. SERS is the English abbreviation of Surface-enhanced Raman scattering, and the Chinese meaning is surface-enhanced Raman scattering. In the magnetic test paper of the present invention, the gold nanorods are vertically arranged on the surface of the superhydrophobic film and self-assembled into an array, and the top of the gold nanorods will have the greatest electromagnetic enhancement, so that the magnetic test paper has excellent SERS enhancement performance . On the surface of the superhydrophobic film, the magnetic compound (Fe 3 O 4 / TiO 2 / Au NRs) are surrounded by a gold nanorod a...

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