Parameter estimation method for bioelectric impedance Cole equation, intelligent equipment and storage medium

A bioimpedance and parameter estimation technology, applied in the field of clinical medicine, can solve the problems of unclear initial guess value and constraint range, poor anti-interference ability, etc., and achieve strong anti-interference ability, good robustness, and accurate ECW and TBW values Effect
CN108852352AActive Publication Date: 2018-11-23MAIDEAN MEDICAL EQUIP SHENZHEN
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
MAIDEAN MEDICAL EQUIP SHENZHEN
Publication Date
2018-11-23

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Abstract

The invention discloses a parameter estimation method for a bioelectric impedance Cole equation, intelligent equipment and a storage medium. The method comprises the steps that according to amplitudevalues and phase values of potential differences measured under frequencies, real parts and imaginary parts of impedance values are calculated; according to the real parts and imaginary parts of the impedance values, an initial guess value and constraint range of each parameter are determined; according to the initial guess value and constraint range of each parameter, fitting parameters and fitting impedance values are determined; according to a threshold of an error sum of squares of the fitting impedance values and measurement values, an optimum fitting parameter value is determined. The parameter estimation method for the bioelectric impedance Cole equation, the intelligent equipment and the storage medium simultaneously use the real parts and imaginary parts of the impedance values, arithmetic solutions of an equation set are solved, the initial guess values and the constraint ranges are estimated to be used for NLLS fitting, and measures for avoiding noise risks are further adopted, the robustness is very good, the capacity of resisting disturbance is high, parameters of the Cole equation can still be fitted and estimated accurately under the serious situation of noise, thereby obtaining more accurate ECW and TBW values.
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Description

technical field

[0001] The invention relates to the field of clinical medicine, in particular to a method for estimating parameters of a bioimpedance Cole equation, an intelligent device and a storage medium. Background technique

[0002] Fluid overload is associated with increased morbidity and mortality in patients with chronic kidney disease, acute kidney injury, or heart failure and critical illness. Therefore, the determination of extracellular fluid has important clinical significance. Bioimpedance is a reliable, non-invasive technique that uses the electrical properties of human tissue to measure extracellular fluid and total body water.

[0003] Cells are the basic structure of biological tissues, composed of extracellular fluid, intracellular fluid, and cell membrane. When biological tissues are in the low frequency region (below 1MHz), the electrical properties of extracellular fluid and intracellular fluid are close to resistance, while the cell membrane can be ...

Claims

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