Parameter estimation method for bioelectric impedance Cole equation, intelligent equipment and storage medium

A bioimpedance and parameter estimation technology, applied in the field of clinical medicine, can solve the problems of unclear initial guess value and constraint range, poor anti-interference ability, etc., and achieve strong anti-interference ability, good robustness, and accurate ECW and TBW values Effect

Active Publication Date: 2018-11-23
MAIDEAN MEDICAL EQUIP SHENZHEN
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Problems solved by technology

[0012] In view of this, a method for estimating parameters of the bioimpedance Cole equation, an intelligent device and a storage medium provided by the present invention can solve the problem that the initial guess value and constraint range of the parameters of the bioimpedance Cole equation in the prior art are not clear, which leads to Poor anti-interference ability, especially under the influence of severe noise, the anti-interference ability is even worse

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  • Parameter estimation method for bioelectric impedance Cole equation, intelligent equipment and storage medium
  • Parameter estimation method for bioelectric impedance Cole equation, intelligent equipment and storage medium
  • Parameter estimation method for bioelectric impedance Cole equation, intelligent equipment and storage medium

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Embodiment Construction

[0053] Below, the present invention will be further described in conjunction with the accompanying drawings and specific implementation methods. It should be noted that, under the premise of not conflicting, the various embodiments described below or the technical features can be combined arbitrarily to form new embodiments. .

[0054] refer to figure 1 , figure 1 It is a flowchart of an embodiment of a method for estimating parameters of a bioimpedance Cole equation in the present invention.

[0055] It should be noted that the bioimpedance Cole equation is where, where, Z(ω) is the impedance, R 0 is the resistance at DC, R ∞ is the resistance at infinite frequency, ω is the angular frequency, τ is the time constant related to the cell membrane, and α is the distribution of the time constant. The above formula is called the Cole equation.

[0056] In step S101, the real part and the imaginary part of the impedance value are calculated according to the amplitude and phas...

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Abstract

The invention discloses a parameter estimation method for a bioelectric impedance Cole equation, intelligent equipment and a storage medium. The method comprises the steps that according to amplitudevalues and phase values of potential differences measured under frequencies, real parts and imaginary parts of impedance values are calculated; according to the real parts and imaginary parts of the impedance values, an initial guess value and constraint range of each parameter are determined; according to the initial guess value and constraint range of each parameter, fitting parameters and fitting impedance values are determined; according to a threshold of an error sum of squares of the fitting impedance values and measurement values, an optimum fitting parameter value is determined. The parameter estimation method for the bioelectric impedance Cole equation, the intelligent equipment and the storage medium simultaneously use the real parts and imaginary parts of the impedance values, arithmetic solutions of an equation set are solved, the initial guess values and the constraint ranges are estimated to be used for NLLS fitting, and measures for avoiding noise risks are further adopted, the robustness is very good, the capacity of resisting disturbance is high, parameters of the Cole equation can still be fitted and estimated accurately under the serious situation of noise, thereby obtaining more accurate ECW and TBW values.

Description

technical field [0001] The invention relates to the field of clinical medicine, in particular to a method for estimating parameters of a bioimpedance Cole equation, an intelligent device and a storage medium. Background technique [0002] Fluid overload is associated with increased morbidity and mortality in patients with chronic kidney disease, acute kidney injury, or heart failure and critical illness. Therefore, the determination of extracellular fluid has important clinical significance. Bioimpedance is a reliable, non-invasive technique that uses the electrical properties of human tissue to measure extracellular fluid and total body water. [0003] Cells are the basic structure of biological tissues, composed of extracellular fluid, intracellular fluid, and cell membrane. When biological tissues are in the low frequency region (below 1MHz), the electrical properties of extracellular fluid and intracellular fluid are close to resistance, while the cell membrane can be ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/053
CPCA61B5/0537A61B5/4881
Inventor 李燕青
Owner MAIDEAN MEDICAL EQUIP SHENZHEN
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