Cell collecting device of membrane-type liquid-based cytology slide processor

Abstract

The invention provides a cell collecting device of a membrane-type liquid-based cytology slide processor. A liquid level sensor connected electrically with a control system is arranged in a filter membrane barrel to transmit a liquid level signal in the filter membrane barrel to the control system to accurately control the action time of a negative pressure air pump so as to collect cells more effectively and safely. The invention also provides a method for collecting the cells by using the cell collecting device in the membrane-type liquid-based cell film maker. The device and the method canadjust the cell collecting time of the membrane-type liquid-based cytology slide processor instantly according to the actual situation of a sample so as to prevent situations of filter membrane explosion, air pump idling or insufficient cell collection.

Description

technical field

[0001] The invention relates to the technical field of liquid-based cell preparation, in particular to a cell collection device of a membrane-type liquid-based cell preparation machine. Background technique

[0002] The liquid-based cell production machine can evenly distribute a thin layer of cells on the carrier, which overcomes the problems of too thick material, cell overlap, blurred background and poor staining in the traditional Pap smear technology, and the liquid-based cell production The chip machine can repeatedly copy the same sample, which is more conducive to the accurate diagnosis and screening of pathological cells. This technology helps to screen abnormal cells, improve the sensitivity and specificity of cervical lesion screening, make it easier to detect early cancers, reduce the incidence of advanced cancers, and reduce the mortality rate of cervical cancer.

[0003] The working principle of the commonly used membrane-type liquid-based cell...

Examples

Embodiment １

[0017] equipment and materials

[0018] Negative pressure air pump: VCH1028 high negative pressure miniature vacuum pump, Chengdu Xinweicheng Technology Co., Ltd.

[0019] Filter cartridge: S-T-003 Xinpai TCT filter cup, 8 μm, American HOLOGIC company

[0020] Liquid level sensor: LDY08 capacitive liquid level sensor, Shenzhen Lynn Technology Co., Ltd.

[0021] This embodiment provides a cell collection device for a membrane-type liquid-based cell slicer, including a storage liquid bottle 1, a membrane filter cartridge 2, a negative pressure air pump 5, and an air pipe 6, and a filter membrane is installed at the bottom of the filter membrane cartridge 2 3. The top is connected to the negative pressure air pump 5 through the air pipe 6, and the negative pressure air pump 5 is electrically connected to the control system. The bottom of the filter membrane cartridge 2 can extend into the storage liquid bottle 1, and the filter membrane cartridge 2 is provided with a liquid leve...

Embodiment 2

[0023] This embodiment provides a cell collection method for a membrane-type liquid-based cell sheet maker, which includes the following steps:

[0024] A liquid level sensor 4 is set in the filter membrane cartridge 2, and the liquid level sensor 4 is electrically connected to the control system;

[0025] Start the negative pressure air pump 5, pump air through the trachea 6, generate negative pressure in the membrane filter cartridge 2, filter the preservation solution into the membrane cartridge 2 through the filter membrane 3, and the cells in the preservation solution are trapped and adsorbed on the filter membrane 3 on the outside;

[0026] During the cell collection process, the liquid level sensor 4 sends the liquid level signal in the filter cartridge 2 to the control system, and when the signal shows that the liquid level in the filter cartridge 2 no longer rises, the operator turns off the negative pressure Air pump 5, stops cell collection.

[0027] The present i...

technical field

[0001] The invention relates to the technical field of liquid-based cell preparation, in particular to a cell collection device of a membrane-type liquid-based cell preparation machine. Background technique

[0002] The liquid-based cell production machine can evenly distribute a thin layer of cells on the carrier, which overcomes the problems of too thick material, cell overlap, blurred background and poor staining in the traditional Pap smear technology, and the liquid-based cell production The chip machine can repeatedly copy the same sample, which is more conducive to the accurate diagnosis and screening of pathological cells. This technology helps to screen abnormal cells, improve the sensitivity and specificity of cervical lesion screening, make it easier to detect early cancers, reduce the incidence of advanced cancers, and reduce the mortality rate of cervical cancer.

[0003] The working principle of the commonly used membrane-type liquid-based cell...

Examples

Embodiment １

[0017] equipment and materials

[0018] Negative pressure air pump: VCH1028 high negative pressure miniature vacuum pump, Chengdu Xinweicheng Technology Co., Ltd.

[0019] Filter cartridge: S-T-003 Xinpai TCT filter cup, 8 μm, American HOLOGIC company

[0020] Liquid level sensor: LDY08 capacitive liquid level sensor, Shenzhen Lynn Technology Co., Ltd.

[0021] This embodiment provides a cell collection device for a membrane-type liquid-based cell slicer, including a storage liquid bottle 1, a membrane filter cartridge 2, a negative pressure air pump 5, and an air pipe 6, and a filter membrane is installed at the bottom of the filter membrane cartridge 2 3. The top is connected to the negative pressure air pump 5 through the air pipe 6, and the negative pressure air pump 5 is electrically connected to the control system. The bottom of the filter membrane cartridge 2 can extend into the storage liquid bottle 1, and the filter membrane cartridge 2 is provided with a liquid leve...

Embodiment 2

[0023] This embodiment provides a cell collection method for a membrane-type liquid-based cell sheet maker, which includes the following steps:

[0024] A liquid level sensor 4 is set in the filter membrane cartridge 2, and the liquid level sensor 4 is electrically connected to the control system;

[0025] Start the negative pressure air pump 5, pump air through the trachea 6, generate negative pressure in the membrane filter cartridge 2, filter the preservation solution into the membrane cartridge 2 through the filter membrane 3, and the cells in the preservation solution are trapped and adsorbed on the filter membrane 3 on the outside;

[0026] During the cell collection process, the liquid level sensor 4 sends the liquid level signal in the filter cartridge 2 to the control system, and when the signal shows that the liquid level in the filter cartridge 2 no longer rises, the operator turns off the negative pressure Air pump 5, stops cell collection.

[0027] The present i...

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