Product used for evaluating effect of propranolol in treatment of infant hemangioma
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A technology of infantile hemangioma and propranolol, applied in the field of medicine, can solve problems such as no breakthrough progress, and achieve a significant effect of rehabilitation
Active Publication Date: 2019-02-26
SHANDONG UNIV QILU HOSPITAL
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In summary, the emergence of PRO provides a certain opportunity for the study of the pathogenesis of IH, but there is still no breakthrough at this stage
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[0043] It should be noted that the following detailed description is exemplary and intended to provide further explanation of the present invention. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs.
[0044] It should be noted that the terminology used here is only for describing specific embodiments, and is not intended to limit exemplary embodiments according to the present invention. As used herein, unless the context clearly dictates otherwise, the singular is intended to include the plural, and it should also be understood that when the terms "comprising" and / or "comprising" are used in this specification, they mean There are features, steps, operations and / or combinations thereof.
[0045] Aiming at the problems raised in the background technology, the present invention provides a product for evaluating the prognosis of infantile heman...
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Abstract
The invention belongs to medical field, and more specifically relates to a product used for evaluating effect of propranolol in treatment of infant hemangioma. The product is a kit, equipment, an operating system, and / or a composition of the kit, the equipment, and the operating system. The product comprises 1, a reagent, an instrument and / or a system used for measuring expressive abundances of ID1 and beta-actin in cells of a measurement object; 2, a module and / or a processor used for calculating ID1 relative expression quantity; and 3, a module and / or a processor used for evaluation of treatment effect of propranolol on infant hemangioma based on the ID1 relative expression quantity. The product is capable of detecting whether drug resistance of infant patients with hemangioma on propranolol is caused, can be used for effective evaluation on treatment effect of propranolol on infant hemangioma, and is capable of providing an effective evaluation method. The evaluation method possesses important meaning in in-time detecting whether drug resistance of patients on propranolol is caused, and adjusting of treatment schemes.
Description
technical field [0001] The invention belongs to the field of medicine, and in particular relates to a product for evaluating the effect of propranolol in treating infantile hemangioma. Background technique [0002] Infantile hemangioma (Infantile Hemangiomas, IH) is a common vascular tumor of infants, the incidence rate of which is as high as 5-10% in ordinary infants, and rises to 30% in premature infants. The onset process is that punctate erythema appears on the skin within a few weeks after delivery, enters a rapid proliferation period, and spontaneously enters a regression period that lasts for several years after about one year of age (Kilcline, C., Frieden, I.J. (2008) Infantile hemangiomas: how common are they? A systematic review of the medical literature. Pediatr Dermatol. 25(2):168-173; Chang, L.C., Haggstrom, A.N., Drolet, B.A., Baselga, E., Chamlin, S.L., Garzon, M.C., Horii, K.A. , Lucky, A.W., Mancini, A.J., Metry, D.W., Nopper, A.J., Frieden, I.J. (2008) Gro...
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