Method for monitoring concentration of glucose solutions based on OCT (optical coherence tomography) technology

Abstract

The invention discloses a method for monitoring the concentration of glucose solutions based on the OCT (optical coherence tomography) technology. According to the method, OCT is mainly utilized to measure the refractive index of glucose, the glucose concentration and the liquid refractive index have a linear relationship at a constant temperature and under constant pressure, and the linear relationship can be used when the concentration change is tested based on the refractive index change. The method specifically includes measuring the refractive indexes of the glucose solutions with different concentrations, and fitting the relationship curve between the glucose and the refractive indexes; filling a fixed pipe cavity with air and an glucose solution with unknown concentration in sequence, determining optical paths d1 and d2 by the OCT, and calculating the refractive index of the unknown glucose solution according to the formula of n=d2 / d1; substituting the refractive index into thepreviously acquired relational expression between the concentration and the refractive index to acquire the concentration of the unknown glucose solution. The method is simple and convenient to operate, accurate in measurement, and capable of quickly measuring the concentration of liquid such as the glucose, thereby fully playing its role in the field of liquid concentration measurement.

Description

technical field [0001] The invention relates to the fields of optical measurement and solution concentration measurement, and relates to realizing the measurement of glucose solution concentration by using an OCT-based technology. Background technique [0002] Solution concentration measurement is a basic process in industrial production. It is widely used in food, chemical, pharmaceutical and other industrial fields. However, the structure of the corresponding device is complex, expensive, and there is no alternative. The measurement principle is mainly to measure the change of the refractive index of the corresponding solution. [0003] The measurement methods of solution concentration include measuring instrument, evaporation method, neutralization titration method for acid or alkali, precipitation method, density method, etc.; but none of them can measure the solution concentration in a fast, real-time, non-contact, automatic and intelligent way. To a lesser extent, the ...

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Problems solved by technology

[0002] Solution concentration measurement is a basic process in industrial production. It is widely used in food, chemical, pharmaceutical and other industrial fields, but the structure of the corresponding device is complex, expensive, and there is no alternative. The measurement principle is mainly to measure the change of the refractive index of the corresponding solution.

[0003] The measurement methods of solution concentration include measuring instrument, evaporation method, neutralization titration method for acid or alkali, precipitation method, density method, etc.; but none of them can measure the solution concentration in a fast, real-time, non-contact, automatic and intelligent way. To a lesser extent, the present invention, based on optical coherence tomography (OCT) technology with appropriate modifications, will provide a competitive new method of measurement

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