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The use of lactoalcohol extract in medicine for treating psoriasis

A technology of lactoalcohol and psoriasis, which is applied in the field of medicine, can solve the problem of less milk, achieve the effect of small side effects, mild medicinal properties, and regulate the body's immunity

Active Publication Date: 2021-09-24
SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are few related researches on lactuary, and the applicant has not seen any reports at home and abroad about the research on the ethanol extract of lactiole in the treatment of psoriasis

Method used

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  • The use of lactoalcohol extract in medicine for treating psoriasis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] Embodiment one: the processing of chicory

[0012] Air-dry the chicory and store at room temperature. Crush 100g of milk lettuce, soak it in 400mL of 70% ethanol, place it in a condensing reflux device and boil it slightly for 2 hours, recover the medicinal solution, and repeat twice; filter the collected medicinal solution and carry out rotary evaporation, and place the obtained concentrate in an oven for drying . The concentrate was dissolved with physiological saline and administered at a dose of 2000 mg / kg.

Embodiment 2

[0013] Example 2: Lacticcoryl alcohol extract has obvious inhibitory effect on psoriasis pruritus

[0014] Establish a psoriasis vulgaris model in mice. After 4 days of administration, observe the scratching situation of the mice within a certain period of time. The experimental results are as follows: figure 1 shown, from figure 1 It can be seen from the figure that the number of scratches of the mice in the experimental group was significantly less than that of the blank control group, and the skin lesions were improved, and the body weight of the mice did not change significantly during the administration period.

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PUM

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Abstract

The invention discloses the effect of the ethanol extract of lactory in treating psoriasis, which can provide a new option for treating psoriasis. Mulgedium tataricum (L.) DC. is a medicinal and edible plant of the genus Mulgedium tataricum in the family Asteraceae. The alcohol extract of milk lettuce can significantly improve the pruritus and skin lesions of psoriasis. The discovery of this therapeutic effect shows that milk lettuce has a good drug prospect, which can provide a certain basis for the development and clinical application of drugs for the treatment of psoriasis .

Description

technical field [0001] The invention relates to the application of lactocoryl alcohol extract in the treatment of psoriasis, which belongs to the technical field of medicine. Background technique [0002] Psoriasis, commonly known as psoriasis, is a chronic inflammatory skin disease with a long course of disease and a tendency to relapse. It is also a polygenic genetic disease that interacts with multiple factors such as genetic factors and environmental factors. The disease covers all groups of people, but it is mainly young and middle-aged, which can greatly affect the physical and mental status of patients. The main features of the disease are erythema and scales. Some studies believe that psoriasis is an immune-mediated inflammatory disease, but the etiology of the disease is complicated, and the current research is not very clear. Therefore, finding a safe and effective drug has become an urgent problem. [0003] Milk lettuce, also known as Mengshan lettuce, Zihuashan...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/28A61P17/06A61P17/04A61P29/00A61P37/02
CPCA61K36/28A61K2236/333A61P17/04A61P17/06A61P29/00A61P37/02
Inventor 梅之南李丹周洢羽张羽王毅覃瑞刘虹
Owner SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES
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