A traditional Chinese medicine composition for treating dilated cardiomyopathy and its application

A technology of dilated cardiomyopathy and composition, applied in the field of traditional Chinese medicine, can solve problems such as lack of consensus

Active Publication Date: 2021-08-10
GUANGANMEN HOSPITAL CHINA ACAD OF CHINESE MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] It can be seen that in the field of TCM treatment of DCM, the treatment principles and methods have different emphases and characteristics, and there is no consensus. More clinical practice and exploration are needed.

Method used

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  • A traditional Chinese medicine composition for treating dilated cardiomyopathy and its application
  • A traditional Chinese medicine composition for treating dilated cardiomyopathy and its application
  • A traditional Chinese medicine composition for treating dilated cardiomyopathy and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0076] Embodiment 1: Patient Tian, ​​female, 40 years old, first visit on March 7, 2017.

[0077] Chief complaint: intermittent wheezing for more than 1 year.

[0078] History of present illness: In March 2016, the patient had wheezing after activities without obvious incentives, and woke up at night, and the symptoms were relieved after systemic treatment. In December 2016, due to recurrent symptoms, he went to the General Hospital of Shenyang Military Region for treatment. Echocardiography showed: left atrium 44mm, left ventricle 56mm, left ventricle posterior wall 10mm, interventricular septal thickness 10mm, EF: 39%, FS: 19%. Tips: Enlarged whole heart, reduced cardiac function; Mitricuspid regurgitation (mild); Pulmonary hypertension (mild). Without special treatment, in order to improve the symptoms, he came to our hospital for outpatient treatment.

[0079] Immediate symptoms: no obvious wheezing, no shortness of breath and fatigue, can lie down at night, no waking up...

Embodiment 2

[0103] Embodiment 2: Patient Wang, male, 47 years old, first visit on December 13, 2014.

[0104] Chief complaint: paroxysmal chest tightness and breathlessness for more than 1 year.

[0105] History of present illness: The patient suffered from chest tightness and breathlessness in 2013 without obvious inducement. Seeing a doctor in the local county people's hospital, echocardiography showed: left atrium 40mm, left ventricle 59mm, right ventricle 18mm, left ventricle posterior wall 7mm, EF: 58%, FS: 29%. Tip: left heart enlargement; mitral regurgitation (mild); tricuspid regurgitation (mild). Conventional treatment showed no significant improvement, so she came to our hospital for outpatient treatment.

[0106] Immediate symptoms: paroxysmal chest tightness, suffocation, no waking up, fatigue, shortness of breath, chills, timid and easy to startle, tinnitus, no dry mouth and bitter mouth, Na Ke Mian An, stools per day, shape, quality, urination .

[0107] Tongue pulse: da...

Embodiment 3

[0125] Embodiment 3: Patient Chang, female, 53 years old, first visit on January 27, 2015.

[0126] Chief complaint: paroxysmal chest tightness and breathlessness for more than 1 year.

[0127] History of present illness: The patient suffered from chest tightness and breathlessness in 2014 without obvious inducement. On January 26, 2015, he went to the 305th Hospital of the Chinese People’s Liberation Army. The echocardiography showed that the whole heart was enlarged, mainly the left heart was enlarged. About 42×61mm, the anteroposterior diameter of the right ventricle is about 33mm; there is no abnormality in the thickness of the ventricular wall and interventricular septum, and the range of motion varies and is generally weakened. Both the anterior and posterior pericardial cavities were probed into liquid dark areas, and the thicknesses were about 5.9mm and 4.8mm, respectively. More trabecular structures were detected in the apex of the right ventricle. The shape and ec...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating dilated cardiomyopathy. The active ingredients of the composition are aconite, dried ginger, licorice, astragalus, Codonopsis radix, Ophiopogon japonicus, schisandra, and cassia twig in a certain weight ratio. , raw oysters and other raw materials. The traditional Chinese medicine composition has the effects of warming yang and dredging channels, promoting blood circulation and removing blood stasis, and has remarkable curative effect on dilated cardiomyopathy.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating dilated cardiomyopathy, which belongs to the field of traditional Chinese medicine. Background technique [0002] Overview: Dilated cardiomyopathy (Dilated Cardiomyopathy, DCM) is a heart disease with the main clinical manifestations of unilateral or bilateral cardiac chamber enlargement, myocardial systolic dysfunction, with or without congestive heart failure, such as chronic cardiac insufficiency , arrhythmia, thromboembolism, sudden death, etc. The domestic epidemiological survey found that the 5-year case fatality rate of DCM was 80%, while the 5-year case fatality rate of foreign DCM was about 50%. The family and society have caused a serious economic burden. At present, the etiology of this disease is unknown, the clinical manifestations are non-specific, and there are no effective treatment methods and drugs. The main clinical treatments are improving heart funct...

Claims

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Application Information

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Patent Type & AuthorityPatents(China)
IPC IPC(8): A61K36/9068A61P9/00A61K35/618
CPCA61K35/618A61K36/344A61K36/481A61K36/484A61K36/54A61K36/57A61K36/575A61K36/65A61K36/71A61K36/714A61K36/752A61K36/79A61K36/804A61K36/8968A61K36/9068A61P9/00A61K2300/00
Inventor李军陈恒文谭雨晴武庆娟田盼盼高健
OwnerGUANGANMEN HOSPITAL CHINA ACAD OF CHINESE MEDICAL SCI