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Traditional Chinese medicinal composition for treating dilated cardiomyopathy, and application thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine, can solve problems such as the lack of consensus

Active Publication Date: 2019-07-05
GUANGANMEN HOSPITAL CHINA ACAD OF CHINESE MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] It can be seen that in the field of TCM treatment of DCM, the treatment principles and methods have different emphases and characteristics, and there is no consensus. More clinical practice and exploration are needed.

Method used

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  • Traditional Chinese medicinal composition for treating dilated cardiomyopathy, and application thereof
  • Traditional Chinese medicinal composition for treating dilated cardiomyopathy, and application thereof
  • Traditional Chinese medicinal composition for treating dilated cardiomyopathy, and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0076] Example 1: The patient Tian, ​​female, 40 years old, was diagnosed for the first time on March 7, 2017.

[0077] Main complaint: Intermittent asthmatic hold for more than 1 year.

[0078] History of present illness: In March 2016, the patient suffered from wheezing and suffocation after activity without obvious inducement, and waking up at night, and the symptoms were relieved by systemic treatment. In December 2016, due to repeated episodes of symptoms, he went to the Shenyang Military Region General Hospital and underwent echocardiography to show: left atrium 44mm, left ventricle 56mm, left ventricular posterior wall 10mm, interventricular septum thickness 10mm, EF: 39%, FS: 19%. Tips: Enlarged whole heart, decreased heart function; mitral valve regurgitation (mild); pulmonary hypertension (mild). No special treatment was given. In order to improve the symptoms, he came to our outpatient clinic.

[0079] Chronic symptoms: no obvious wheezing, no shortness of breath, fatigu...

Embodiment 2

[0103] Example 2: Patient Wang, male, 47 years old, was first diagnosed on December 13, 2014.

[0104] Main complaint: Paroxysmal chest tightness and suffocation for more than 1 year.

[0105] History of present illness: The patient had chest tightness and suffocation in 2013 with no obvious cause. At the local county people’s hospital, the echocardiography showed: left atrium 40mm, left ventricle 59mm, right ventricle 18mm, left ventricular posterior wall 7mm, EF: 58%, FS: 29%. Tips: The left heart is enlarged; mitral regurgitation (mild); tricuspid regurgitation (mild). There was no obvious improvement in conventional treatment, so he came to our outpatient clinic.

[0106] Chronic symptoms: paroxysmal chest tightness, suffocation, no awakening, fatigue, shortness of breath, chills, timid and easy to startle, tinnitus, no dry mouth, painful mouth, napkinol, bowel movements, forming, good quality, small .

[0107] Tongue and pulse: dark red tongue, thin yellow coating, thin pulse....

Embodiment 3

[0125] Example 3: Patient Chang, female, 53 years old, was first diagnosed on January 27, 2015.

[0126] Main complaint: Paroxysmal chest tightness and suffocation for more than 1 year.

[0127] History of present illness: The patient had chest tightness and suffocation in 2014 without any obvious cause. On January 26, 2015, he went to the 305th Hospital of the Chinese People's Liberation Army. The echocardiography showed that the whole heart was enlarged, mainly the left heart. The inner diameter of the left atrium was about 53×57×72mm, the anteroposterior diameter of the left ventricle was about 62mm, and the right atrium Approximately 42×61mm, the anteroposterior diameter of the right ventricle is approximately 33mm; the thickness of the ventricular wall and interventricular septum is not abnormal, and the amplitude of motion varies widely and generally weakened. Both the front and back pericardial cavities explored the liquid dark area, and the thickness was about 5.9mm and 4....

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Abstract

The invention discloses a traditional Chinese medicinal composition for treating dilated cardiomyopathy. The composition is prepared from the prepared root of common monkshood, dried ginger, licoriceroots, the root of Mongolian milkvetch, the root of hairy asiabell, the root of dwarf lilyturf, fruits of Chinese magnoliavine, cassia twigs and raw oysters according to a certain weight proportion. The traditional Chinese medicinal composition has the functions of warming Yang, dredging collaterals, promoting blood circulation and removing blood stasis, and has a remarkable curative effect on thedilated cardiomyopathy.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine composition for treating dilated cardiomyopathy and belongs to the field of traditional Chinese medicine. Background technique [0002] Summary: Dilated Cardiomyopathy (Dilated Cardiomyopathy, DCM) is a heart disease whose main clinical manifestations are unilateral or bilateral enlargement of the heart chambers, decreased myocardial contractility, with or without congestive heart failure, such as chronic cardiac insufficiency , Arrhythmia, thromboembolism, sudden death, etc. The domestic epidemiological survey found that the 5-year mortality rate of DCM was 80%, while the 5-year mortality rate of foreign DCM was about 50%. The American epidemiological survey found that the prevalence of advanced DCM was about 36.5 / 100,000. The family and society have caused a serious economic burden. At present, the cause of this disease is unknown, the clinical manifestations are not specific, and there are no spec...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P9/00A61K35/618
CPCA61K35/618A61K36/344A61K36/481A61K36/484A61K36/54A61K36/57A61K36/575A61K36/65A61K36/71A61K36/714A61K36/752A61K36/79A61K36/804A61K36/8968A61K36/9068A61P9/00A61K2300/00
Inventor 李军陈恒文谭雨晴武庆娟田盼盼高健
Owner GUANGANMEN HOSPITAL CHINA ACAD OF CHINESE MEDICAL SCI
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