Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A kind of small molecular toxin isolated and purified from the crude venom of Edenia grandis and its application

A technology for separation and purification, and it is applied in the application, peptide, biocide and other directions to achieve the effect of strong effect and reliable results.

Active Publication Date: 2022-04-15
HUNAN NORMAL UNIVERSITY
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At the same time, there is no report on the selective effect of these acetylpolyamine small molecules on insect sodium channels

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of small molecular toxin isolated and purified from the crude venom of Edenia grandis and its application
  • A kind of small molecular toxin isolated and purified from the crude venom of Edenia grandis and its application
  • A kind of small molecular toxin isolated and purified from the crude venom of Edenia grandis and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0029] The present invention provides a small molecular toxin isolated and purified from the crude venom of E. grandis, the small molecule toxin isolated and purified from the crude venom of E. Ammonium small-molecule toxin, the relative molecular weight is 757.5112, nuclear magnetic resonance structure analysis, the molecular formula of the small-molecule toxin isolated and purified from the crude venom of Arachnid grandis is C 36 h 64 o 5 N 13 , whose structural formula is:

[0030]

[0031] The application of the small-molecule toxin isolated and purified from the crude venom of E. grandina provided by the present invention in insecticides or in neurobiological reagents and / or medicines, especially to block or completely block insect sodium ion channels way of application as a pesticide. When the small-molecule toxin isolated and purified from the crude venom of E. macula completely blocks the insect sodium ion channel, the concentration of the small-molecule toxin i...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention belongs to the technical field of chemistry and chemical engineering, and relates to a small-molecule toxin isolated and purified from the crude venom of E. grandis, and its application. The small-molecule toxin separated and purified from the crude venom of E. grandis is a quaternary ammonium small-molecule toxin. The relative molecular weight is 757.5112, and the nuclear magnetic resonance structure analysis shows that the molecular formula of the small molecular toxin isolated and purified from the crude venom of Arachnid grandis is C 36 h 64 o 5 N 13 , The present invention provides a small molecular toxin isolated and purified from the crude venom of E. grandina, which has selective activity on insects, is less affected by pH, has stronger effect and more stable effect, and its application.

Description

technical field [0001] The invention belongs to the technical field of chemistry and chemical engineering, and relates to a small-molecule toxin and its application, in particular to a small-molecule toxin separated and purified from the crude venom of E. grandis, and its application. Background technique [0002] The large-bellied garden spider (Araneus ventricosus) is a medium-sized spider that feeds on insects, and belongs to the phylum Arthropoda, Araneus, Aranea, Orbidae, and Orb genus in classification. The arachnid is one of the most widely distributed spiders in the world, and its venom contains a large number of toxic components that can anesthetize or kill insects. Explore the structural and functional characteristics of these small-molecule toxins isolated and purified from the crude venom of E. grandis, and screen out precursor molecules that may be used as neurobiological research tool reagents, drugs and insecticides. At present, there are very few studies on ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C07K5/078A01N47/44A01P7/04
CPCC07K5/06139A01N47/44
Inventor 段志贵刘凯
Owner HUNAN NORMAL UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com