Method for detecting TH gene SNP locus related to opioid dependence and application thereof
A technology of material dependence and detection method, which is applied in the direction of microbial determination/inspection, biochemical equipment and methods, etc., can solve the problems of unreported relationship of dependence, achieve accurate typing results, fast genotyping, and application prospects broad effect
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[0028] The present invention will be further described below in conjunction with the accompanying drawings and embodiments, which are to explain the present invention rather than limit the protection scope of the present invention.
[0029] In the present invention, the sequence of the SNP site rs10770140 is studied, and the genotype of the subject's TH gene rs10770140 polymorphic site is determined by extracting human genomic DNA, and it is found that the polymorphic site is closely related to the subject's susceptibility to OD: When the genotype of TH gene rs10770140 polymorphic site is C / C homozygous, the subject has the highest susceptibility; when the genotype of TH gene rs10770140 polymorphic site is C / T heterozygous, the subject's susceptibility Higher; when the genotype of TH gene rs10770140 polymorphic site is T / T homozygous, the susceptibility of the subject is the lowest. Based on the above findings, the present invention proposes a screening method and screening ki...
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