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Compound preparation for treating less semen amount, and preparation method thereof

A compound preparation and semen volume technology, which is applied in the direction of medical preparations containing active ingredients, drug combinations, and pharmaceutical formulas, can solve problems affecting work and life rest time, bitter and unpleasant smell of traditional Chinese medicine, and unacceptable to patients, and achieve the production process Mature, lower blood fat, convenient to take effect

Pending Publication Date: 2019-11-08
山东腾贵医药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The treatment method for low semen volume is mainly traditional Chinese medicine conditioning, because Chinese medicine needs to be tortured to fully exert its efficacy, so patients need a fixed time every day to decoct Chinese medicine, which affects normal work, life and rest time; at the same time, Chinese medicine is bitter and unpleasant. It is difficult for patients to accept, and "the medicine is three-point poisonous", and the conditioning of traditional Chinese medicine also has certain side effects on the body

Method used

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  • Compound preparation for treating less semen amount, and preparation method thereof
  • Compound preparation for treating less semen amount, and preparation method thereof
  • Compound preparation for treating less semen amount, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Step 1: Weigh each raw material for later use:

[0033]

[0034] Step 2: Freeze-dry the mulberry, wolfberry, ginseng, cinnamon, and Cordyceps militaris weighed in step 1, crush them to 60-200 mesh, and mix them evenly for later use;

[0035] Step 3: Extract the mixture of Step 2 with ethanol solution, combine the filtrates, filter and concentrate under reduced pressure to obtain the extract, the mass ratio of the mixture to ethanol is 1:8, and the extraction conditions are: extract at 50-58°C 3 times, each extraction time is 1-1.5h, and the ethanol solution is an aqueous ethanol solution with a volume fraction of 60-80%

[0036] Step 4: The extract obtained in the step 3 is dried, pulverized, fully mixed with the remaining raw materials of the formula, passed through a 10-20 mesh sieve, and granulated to obtain a compound preparation for treating a small amount of semen;

[0037] Step 5: Packing, testing, and storing the compound preparation obtained in Step 4.

Embodiment 2

[0039] Step 1: Weigh each raw material for later use:

[0040]

[0041] Step 2: Freeze-dry the mulberry, wolfberry, ginseng, cinnamon, and Cordyceps militaris weighed in step 1, crush them to 60-200 mesh, and mix them evenly for later use;

[0042] Step 3: extract the mixture of the step 2 with ethanol solution, combine the filtrates, filter and concentrate under reduced pressure to obtain the extract, the mass ratio of the mixture and ethanol is 1:9, and the extraction conditions are: extract at 50-58°C 3 times, each extraction time is 1-1.5h, and the ethanol solution is an aqueous ethanol solution with a volume fraction of 60-80%

[0043] Step 4: The extract obtained in the step 3 is dried, pulverized, fully mixed with the remaining raw materials of the formula, passed through a 10-20 mesh sieve, and granulated to obtain a compound preparation for treating a small amount of semen;

[0044] Step 5: Packing, testing, and storing the compound preparation obtained in Step 4....

Embodiment 3

[0046] Step 1: Weigh each raw material for later use:

[0047]

[0048] Step 2: Freeze-dry the mulberry, wolfberry, ginseng, cinnamon, and Cordyceps militaris weighed in step 1, crush them to 60-200 mesh, and mix them evenly for later use;

[0049] Step 3: Extract the mixture of Step 2 with ethanol solution, combine the filtrates, filter and concentrate under reduced pressure to obtain the extract, the mass ratio of the mixture to ethanol is 1:8, and the extraction conditions are: extract at 50-58°C 3 times, each extraction time is 1-1.5h, and the ethanol solution is an aqueous ethanol solution with a volume fraction of 60-80%

[0050] Step 4: The extract obtained in the step 3 is dried, pulverized, fully mixed with the remaining raw materials of the formula, passed through a 10-20 mesh sieve, and granulated to obtain a compound preparation for treating a small amount of semen;

[0051] Step 5: Packing, testing, and storing the compound preparation obtained in Step 4.

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Abstract

The present invention discloses a compound preparation for treating less semen amount, and a preparation method thereof. Mulberries, Chinese wolfberry fruits, ginseng, cortex cinnamomi and cordyceps militaris are freeze-dried, the freeze-dried materials are crushed into powder, then the powder is extracted with an ethanol solution, and after filtrates are blended, filtering and concentrating underreduced pressure are conducted to obtain extractum; then the obtained extractum is dried, crushed and fully mixed with residual raw materials in the formula, sieving by a 10-20 mesh sieve is conducted, granule-separating is conducted to obtain a compound preparation for treating less semen amount, and finally, the obtained compound preparation is packaged, inspected and put into a storage. The prepared compound preparation is granules and convenient for patients to eat, also has tastes easy for accept, and is small in side effect of the raw materials and good in effects.

Description

technical field [0001] The present invention relates to the field of preparation of compound preparations, in particular to a compound preparation for treating low semen volume and a preparation method. Background technique [0002] At present, in infertility clinics, low semen volume is a common problem in men. According to the book "Infertility Therapeutics" published by Shanghai Science and Technology Publishing House: the normal semen volume of men is 2-6ml per ejaculation. If it is less than 2ml, it can be considered that the amount of semen is too low. If the amount of semen is less than 2ml in three or more repeated inspections, the diagnosis can be established. Low semen volume in men can affect fertility. [0003] According to clinical observation and research, it is found that the reasons for the low amount of semen are mainly due to the following points: (1) autoimmune factors, anti-sperm antibodies can affect the production and delivery of sperm; (2) varicocele,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/01A61K9/16A61P15/08A61K31/045
CPCA61K9/1623A61K31/045A61K36/605A61K36/815A61K36/258A61K36/54A61K36/068A61K38/012A61P15/08
Inventor 田友李嫦娥刘燕红平国强
Owner 山东腾贵医药有限公司
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