Preparation method and application of anti-chapped compound traditional Chinese medicine liposome

Abstract

The invention discloses a preparation method and application of anti-chapping compound traditional Chinese medicine liposome. The preparation method comprises: selecting aloe vera: calamus: chamomile: kudingcha: cinnamon: myrrh: dandelion with a weight ratio of 1‑3: 3‑4: 4‑5: 2‑4: 1‑2: 1‑2: 1‑3, carry out heating and reflux extraction with ethanol, filter and absorb with activated carbon to obtain a light yellow-green compound Chinese medicine extract; Turbid liquid, while keeping the temperature between 55-65°C; take part of the suspension, quickly inject it into the compound Chinese medicine extract, heat and stir at 40-50°C to volatilize to the original weight of the compound Chinese medicine extract, and obtain the compound Chinese medicine liposome . The compound Chinese medicine extract is made into liposomes, and there is a proven drug delivery mechanism. The structure of the liposome phospholipid bilayer is similar to that of the cell membrane, which can enhance transdermal absorption, protect active substances and release slowly, without Antioxidants need to be added to ensure the final effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine liposome, which belongs to the technical field of traditional Chinese medicine formula products, in particular to a preparation method and application of a compound traditional Chinese medicine liposome for preventing chapping. Background technique [0002] Chapped disease, also known as chapped hands and feet, is a common skin disease, which refers to a disease of dry skin and linear fissures on the skin of hands and feet due to various reasons. It mainly occurs in the cold regions of northern my country, and there are many patients. Due to the cold winter, there is little sweating, frequent friction, and the skin loses moisture and dryness to form chapped skin. It is more common in palms, ten fingertips, sides of hands, sides of feet, heels, children's faces, etc. Fissures of different lengths and depths can be seen, and deep ones may have bleeding and severe pain. [0003] In the past ten year...

AI Technical Summary

Problems solved by technology

However, if it is used as a wound healing ingredient, it needs to be added in a high concentration dose. Long-term storage will easily cause the appearance of the paste to gradually turn yellow, and the effect will gradually weaken. Therefore, when designing the formula, pigments are generally added to cover up the possible discoloration in the future.

[0008] As the active ingredient of the compound Chinese medicine extract, it is also easy to be oxidized and lose its activity. Therefore, it is necessary to add some antioxidants to maintain its activity. At the same time, because of the lack of drug delivery mechanism, most of the active ingredients stay in the paste and really enter the cells. There are very few active ingredients involved in skin repair function, so the effect is not satisfactory and needs to be improved

Images