A kind of long-acting liquid gel containing rose essential oil and its preparation method and application

A technology of rose essential oil and gel, applied in the field of medicine, can solve the problems of no inflammatory injury such as ulcers, no wound healing of rose essential oil, etc., to achieve the effects of promoting wound healing, relieving wound pain, and maintaining natural elasticity
CN112190504BActive Publication Date: 2022-08-09SHAOXING UNIVERSITY +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SHAOXING UNIVERSITY
Publication Date
2022-08-09

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Abstract

The invention provides a long-acting liquid gel containing rose essential oil, a preparation method and application thereof, wherein the liquid gel contains phospholipid (PC), polyglycerol fatty acid ester (PG), rose essential oil (REO) and an organic solvent. The advantages of the long-acting liquid gel for treating oral wounds (especially oral ulcers) provided by the present invention are: first, the liquid gel of the present invention is a low-viscosity flowing liquid before use, and when it encounters an aqueous solution after use, it is A high-viscosity gel is formed, which is convenient for filling and using local cavities of the body, and has a long duration of action; secondly, the liquid gel of the present invention is rich in natural rose essential oil, fused with a variety of polyglycerol derivatives as raw materials, and has no immunogenicity. Good biodegradability, can promote wound healing, relieve wound pain, and can further restore and maintain the natural elasticity of the skin; third, the liquid gel of the present invention does not contain any preservatives, but the validity period is greater than 3 years, and within 5 years Product performance has not changed.
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Description

technical field

[0001] The invention belongs to the technical field of medicine, and particularly relates to a long-acting liquid gel containing rose essential oil and a preparation method and application thereof. Background technique

[0002] For conventional drug delivery systems, multiple doses can be administered to maintain high blood drug concentrations for a long time. However, for parts such as tissue space, organ surface, joint cavity, oral cavity, etc., which are hidden and filled with body fluids, it is almost impossible to continuously administer multiple doses, and it is difficult to maintain the blood drug concentration; and for local lesions, it is not medically recommended for the whole body. Drugs for treatment can easily lead to adverse reactions. Therefore, there is an urgent need for a long-acting in situ sustained and controlled release pharmaceutical preparation that can be easily operated.

[0003] At present, the gel products on the market are gener...

Claims

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