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Traditional Chinese medicine composition for treating rheumatism and rheumatoid and preparation method thereof

A technology of rheumatoid and composition, which is applied in the field of rheumatoid rheumatoid traditional Chinese medicine composition and its preparation, which can solve the problems of large side effects and intolerance of patients, achieve less damage, inhibit swelling of the soles of the feet, and treat rheumatoid rheumatoid diseases Effect

Inactive Publication Date: 2021-01-29
李明昊
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Rheumatic rheumatoid diseases are usually treated with non-steroidal anti-inflammatory drugs and hormone therapy, which have severe side effects and are difficult for patients to tolerate

Method used

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  • Traditional Chinese medicine composition for treating rheumatism and rheumatoid and preparation method thereof
  • Traditional Chinese medicine composition for treating rheumatism and rheumatoid and preparation method thereof
  • Traditional Chinese medicine composition for treating rheumatism and rheumatoid and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Composition of raw materials (parts by weight): 5 parts of Clematis, 5 parts of Radix Wujiapi, 5 parts of Qiannianjian, 1 part of Albino chinensis, 5 parts of Artemisia annua, 2 parts of Miltonia Spatholobus, 1 part of Atractylodes macrocephala, 7 parts of Cuscuta , 2 parts of Asarum, 1 part of Fangfeng, and 10 parts of Tripterygium wilfordii.

[0029] Preparation:

[0030] S1. Weigh Clematis, wash, dry, slice, mix well with rice wine, the solid-to-liquid ratio is 1:2g / mL, moisten thoroughly, put it in a pot and fry it dry with a slow fire, take it out, and let it cool;

[0031] S2. Washing, drying, and pulverizing the Radix Acanthopanax, Artemisia annua, and Spatholobus Spatholobus respectively, and then mixing them, extracting them with supercritical fluid, and drying them to obtain an extract;

[0032] The conditions of supercritical fluid extraction are pressure 25MPa, temperature 40°C, time 120min, entrainer is ethanol solution, the content of ethanol in the ethan...

Embodiment 2

[0037] Composition of raw materials (parts by weight): 25 parts of Clematis, 15 parts of Wujiapi, 10 parts of Qiannianjian, 5 parts of Albino chinensis, 10 parts of Artemisia annua, 5 parts of Spatholobus, 3 parts of Atractylodes macrocephala, 12 parts of Cuscuta , 5 parts of Asarum, 3 parts of Fangfeng, 20 parts of Tripterygium wilfordii.

[0038] Preparation:

[0039] S1. Weigh Clematis, wash, dry, slice, mix well with rice wine, the solid-to-liquid ratio is 1:5g / mL, moisten thoroughly, put it in a pot and fry it dry with a slow fire, take it out, and let it cool;

[0040] S2. Washing, drying, and pulverizing the Radix Acanthopanax, Artemisia annua, and Spatholobus Spatholobus respectively, and then mixing them, extracting them with supercritical fluid, and drying them to obtain an extract;

[0041] The conditions of supercritical fluid extraction are pressure 35MPa, temperature 50°C, time 200min, entrainer is ethanol solution, the content of ethanol in the ethanol solution...

Embodiment 3

[0046] Composition of raw materials (parts by weight): 10 parts of Clematis clematis, 7 parts of Wujiapi, 6 parts of Qiannianjian, 2 parts of Albadodon japonicus, 6 parts of Artemisia annua, 3 parts of Milletanus, 1.5 parts of Atractylodes macrocephala, 9 parts of Cuscuta , Asarum 3 parts, Fangfeng 1.5 parts, Tripterygium wilfordii 12 parts.

[0047] Preparation:

[0048] S1. Weigh Clematis, wash, dry, slice, mix well with rice wine, the solid-to-liquid ratio is 1:3g / mL, moisten thoroughly, put it in a pot and fry it dry with a slow fire, take it out, and let it cool;

[0049] S2. Washing, drying, and pulverizing the Radix Acanthopanax, Artemisia annua, and Spatholobus Spatholobus respectively, and then mixing them, extracting them with supercritical fluid, and drying them to obtain an extract;

[0050] The conditions of supercritical fluid extraction are pressure 27MPa, temperature 42°C, time 140min, entrainer is ethanol solution, the content of ethanol in the ethanol soluti...

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Abstract

The invention provides a traditional Chinese medicine composition for treating rheumatism and rheumatoid arthritis and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following raw materials of radix clematidis, cortex acanthopanacis, obscured homalomena rhizome, densefruit pittany herb, sweet wormwood herb, caulis spatholobi, bighead atractylodes rhizome, semen cuscutae, herba asari, divaricate saposhnikovia root and tripterygium wilfordii. The traditional Chinese medicine composition disclosed by the invention can be used for remarkably inhibiting plantar swelling of a collagen arthritis model rat. The traditional Chinese medicine composition disclosed by the invention has a good application prospect when being used as a medicine composition or an active part for preparing medicines for treating rheumatoid diseases.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating rheumatoid rheumatism and a preparation method thereof. Background technique [0002] Rheumatoid rheumatoid disease belongs to the category of arthralgia in traditional Chinese medicine in my country. Its main symptoms are pain, soreness, heaviness, numbness, difficulty in flexion and extension, or joint swelling in muscles, joints, and bones. It is one of the persistent diseases that seriously endanger human health. In recent years, the incidence rate has increased year by year, and the disability rate has also increased year by year. Generally, the course of the disease is long. Due to the diversity of clinical manifestations, traditional Chinese medicine often combines them according to different clinical symptoms. If the pathogenic factors are on the surface or the pain is on the upper part, it shou...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/888A61P19/02A61P29/00
CPCA61K36/10A61K36/238A61K36/254A61K36/268A61K36/282A61K36/284A61K36/37A61K36/39A61K36/43A61K36/486A61K36/716A61K36/888A61K2236/15A61K2236/331A61K2236/333A61P19/02A61P29/00A61K2300/00
Inventor 李明昊冯丽丽
Owner 李明昊