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A method for detection and identification of covid-19 based on microscopic hyperspectral

A technology of COVID-19 and identification method, which is applied in the field of COVID-19 detection and identification based on microscopic hyperspectral, can solve the problem of new coronavirus pneumonia that cannot be ruled out, and achieve the effect of rapid and efficient deployment

Active Publication Date: 2022-07-22
JILIN UNIV
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  • Abstract
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AI Technical Summary

Problems solved by technology

[0002] The current detection method suitable for large-scale applications is to detect the new coronavirus through RT-PCR reverse transcription polymerase chain reaction. The positive rate of nucleic acid detection of throat swabs and nasopharyngeal swabs is now about 30% to 40%. Negative tests cannot rule out novel coronavirus pneumonia, even if multiple tests are negative. Usually, it takes 4 to 6 hours to obtain the results, and the detection accuracy is about 80% to 90%, which requires the use of more expensive equipment to obtain test results

Method used

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  • A method for detection and identification of covid-19 based on microscopic hyperspectral
  • A method for detection and identification of covid-19 based on microscopic hyperspectral
  • A method for detection and identification of covid-19 based on microscopic hyperspectral

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specific Embodiment approach

[0063] S1. The tested person gargles with normal saline, and the testing person uses the "pharyngeal swab" method to obtain the sample to be tested.

[0064] S2. Separate the sample to be detected into sample A and sample B. Sample A is marked with a fluorescent reagent and configured as a standard sample to be detected, and then scanned by a PCR fluorescence scanner, and the amplification curve is obtained by computer analysis and the identification result αA is output, wherein α is a positive coefficient less than 1, and A is a Boolean number.

[0065] S3. Configure the separated sample B as a standard sample to be detected, and send the obtained standard detection sample B into the dark-field hyperspectral microscopic analysis and detection device, and the standard sample is focused and identified by the lens, and the hyperspectral spectrum is obtained. data.

[0066] S4. Perform image preprocessing and spectral processing on the data obtained in S3, and identify and analy...

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Abstract

The invention discloses a method for detecting and identifying COVID-19 based on microscopic hyperspectral, and relates to the field of virus detection. The specific method is as follows: the test personnel obtain the test sample from the mouth of the person to be tested by the method of "throat swab", separate and add reagents through the separation device to prepare two standard test samples, and then obtain the conventional diagnostic results and The detection and identification results obtained quickly by microscopic hyperspectral technology, the latter of which can be independently used for diagnostic detection, and some of the detection processes are fully compatible with existing PCR detection technology. On this basis, the detection data obtained above are sent to the big data platform, and the big database platform provides the comparative analysis results and displays the final results. The invention is a fast and efficient method, usually only takes 15-20 minutes, expands the existing detection technology, improves the accuracy of virus detection, and greatly improves the efficiency of epidemic prevention work.

Description

technical field [0001] The present invention relates to the technical field of virus detection, and more particularly, to a method for detecting and identifying COVID-19 based on microscopic hyperspectral. Background technique [0002] The current detection method suitable for large-scale applications is to detect the new coronavirus by RT-PCR reverse transcription polymerase chain reaction. The nucleic acid detection rate of throat swabs and nasopharyngeal swabs is now about 30% to 40%, while A negative test cannot rule out new coronavirus pneumonia, even if multiple tests are negative, it cannot be ruled out. Usually, the test takes 4 to 6 hours to obtain the result, and the detection accuracy rate is roughly 80% to 90%. device to obtain test results. SUMMARY OF THE INVENTION [0003] In order to further improve the detection accuracy and greatly shorten the detection time, the present invention provides a method for detecting and identifying COVID-19 based on microscop...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06V20/69G06V10/143G06T7/136G06T7/194C12Q1/70C12Q1/686C12R1/93
CPCG06T7/194G06T7/136C12Q1/701C12Q1/686G06V20/69G06V10/143C12Q2521/537C12Q2563/107
Inventor 李文军龙伟
Owner JILIN UNIV
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