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COVID-19 detection and identification method based on microscopic hyperspectrum

A technology of COVID-19 and identification method, which is applied in the field of detection and identification of COVID-19 based on microscopic hyperspectral, can solve problems such as new coronavirus pneumonia cannot be ruled out, and achieve the effect of clear image details

Active Publication Date: 2021-03-26
JILIN UNIV
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  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The current detection method suitable for large-scale applications is to detect the new coronavirus through RT-PCR reverse transcription polymerase chain reaction. The positive rate of nucleic acid detection of throat swabs and nasopharyngeal swabs is now about 30% to 40%. Negative tests cannot rule out new coronavirus pneumonia, even if multiple tests are negative, it usually takes 4 to 6 hours to obtain the results, and the detection accuracy is about 80% to 90%, requiring the use of more expensive equipment to obtain test results

Method used

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  • COVID-19 detection and identification method based on microscopic hyperspectrum
  • COVID-19 detection and identification method based on microscopic hyperspectrum
  • COVID-19 detection and identification method based on microscopic hyperspectrum

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specific Embodiment approach

[0063] S1. The tested person rinses his mouth with normal saline, and the testing personnel use the method of "throat swab" to obtain the sample to be tested.

[0064] S2. Separate the sample to be detected into sample A and sample B. Sample A is marked with a fluorescent reagent and configured as a standard sample to be detected, and then scanned by a PCR fluorescent scanner, and the amplification curve is obtained by computer analysis and the recognition result αA is output, where α is a positive coefficient less than 1, and A is a Boolean number.

[0065] S3. Configure the separated sample B as a standard sample to be tested, and send the obtained standard test sample B into the dark field hyperspectral microanalysis detection device, and use the lens to focus and identify the standard sample, and obtain hyperspectral data.

[0066] S4, image preprocessing and spectral processing are carried out to the data obtained in S3, in conjunction with the sample in the database, sp...

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Abstract

The invention discloses a COVID19 detection and identification method based on microscopic hyperspectrum, and relates to the field of virus detection. The method specifically comprises the following steps: obtaining a detection sample from the mouth of a person to be detected by a detector through a throat swab method, separating through a separation device, adding a reagent to prepare two standard detection samples, and then respectively obtaining a conventional diagnosis result through PCR analysis and a detection identification result quickly obtained through a microscopic hyperspectral technology, wherein the latter can be independently used for diagnosis and detection, and part of the detection process is comprehensively compatible with the existing PCR detection technology. And on the basis, the obtained detection data is sent to a big data platform, a comparison and analysis result is given by a big database platform, and a final result is displayed. The invention is a rapid andefficient method, only 15-20 min is needed generally, the existing detection technology is expanded, the virus detection accuracy is improved, and the epidemic prevention work efficiency is greatly improved.

Description

technical field [0001] The invention relates to the technical field of virus detection, more specifically, to a method for detecting and identifying COVID-19 based on microscopic hyperspectral. Background technique [0002] The current detection method suitable for large-scale applications is to detect the new coronavirus through RT-PCR reverse transcription polymerase chain reaction. The positive rate of nucleic acid detection of throat swabs and nasopharyngeal swabs is now about 30% to 40%. Negative tests cannot rule out new coronavirus pneumonia, even if multiple tests are negative, it usually takes 4 to 6 hours to obtain the results, and the detection accuracy is about 80% to 90%, requiring the use of more expensive The device can obtain the test result. Contents of the invention [0003] In order to further improve the detection accuracy and greatly shorten the detection time, the present invention provides a method for detecting and identifying COVID-19 based ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06K9/00G06K9/20G06T7/136G06T7/194C12Q1/70C12Q1/686C12R1/93
CPCG06T7/194G06T7/136C12Q1/701C12Q1/686G06V20/69G06V10/143C12Q2521/537C12Q2563/107
Inventor 李文军龙伟
Owner JILIN UNIV
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