Application of cubilose in preparation of medicine for treating ulcerative colitis

A technology for ulcerative colitis and drugs, applied in the field of pharmacology, can solve problems such as lack of drug efficacy and mechanism of action analysis

Pending Publication Date: 2021-06-04
厦门市燕之屋丝浓食品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is a lack of relevant drug

Method used

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  • Application of cubilose in preparation of medicine for treating ulcerative colitis
  • Application of cubilose in preparation of medicine for treating ulcerative colitis
  • Application of cubilose in preparation of medicine for treating ulcerative colitis

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Embodiment Construction

[0023] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only some of the embodiments of the present invention, but not all of them. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0024] For a better understanding of the present invention, the present invention will be further specifically described below through the following examples, but it should not be construed as a limitation of the present invention. For some non-essential improvements and adjustments made by those skilled in the art according to the above-mentioned content of the invention, It is also considered to fall within the protection scope of the present invention.

[0025] 1. Experimental materials

[0026] (1) Experimental drugs and reagen...

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Abstract

The invention belongs to the technical field of pharmacology, and discloses application of cubilose in preparation of a medicine for treating ulcerative colitis. The medicine in the application can reduce MPO activity and IL-1beta and TNF-alpha contents in colon tissues of mice, enhance the resistance of organisms to external stimulating factors, alleviate weight loss of the mice due to DSS induction, improve colitis, reduce the level of proinflammatory factors, effectively relieve symptoms and inflammatory indexes of the ulcerative colitis, and provides a new thought for the development of medicines for treating the ulcerative colitis.

Description

technical field [0001] The invention belongs to the technical field of pharmacy, and in particular relates to the application of bird's nest in preparing medicine for treating ulcerative colitis. Background technique [0002] Ulcerative colitis (UC) is a chronic, idiopathic inflammatory disease that is always associated with mucosal inflammation, usually starting from the rectum and extending to the proximal colon, and lesions are more common in the colon. It mostly occurs in adults aged 30 to 40, and severe cases can cause disability. About 15% of UC patients need to undergo colectomy. According to relevant statistics, the annual direct or indirect treatment costs for UC in Europe and the United States are 1.25-2.91 billion euros and 810-14.9 billion U.S. dollars, respectively. [0003] However, the etiology and pathogenesis of ulcerative colitis are still not very clear. It is generally believed that the etiology of UC may be related to environmental factors, genetic fac...

Claims

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Application Information

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IPC IPC(8): A61K35/57A61P1/04
CPCA61K35/57A61P1/04
Inventor 范群艳李耿赖小平邝卫红樊耀华柳训才李有泉王雅馨
Owner 厦门市燕之屋丝浓食品有限公司
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