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Thyroid malignant tumor diagnosis system based on open-type ion source

A malignant tumor, diagnosis system technology, applied in the field of computer-aided diagnosis system, can solve the problem that the method of image diagnosis cannot provide direct evidence, and achieve the effect of improving diagnosis efficiency and easy processing

Pending Publication Date: 2021-10-19
SHIMADZU (CHINA) CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, diagnostic imaging approaches are not able to provide direct evidence

Method used

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  • Thyroid malignant tumor diagnosis system based on open-type ion source
  • Thyroid malignant tumor diagnosis system based on open-type ion source
  • Thyroid malignant tumor diagnosis system based on open-type ion source

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0102] Pretreatment method of thyroid puncture fluid

[0103] 1) Add 20mL of BD preservation solution containing puncture solution into a centrifuge tube, and centrifuge to obtain a supernatant;

[0104] 2) Take 2 mL of supernatant, add it again to a centrifuge tube containing 2 mL of ethanol and 0.007 mL of formic acid, and vortex to mix.

Embodiment 2

[0106] Pretreatment method of thyroid puncture fluid

[0107] 1) Add 20 mL of liquid-based cell preservation solution containing puncture solution into a centrifuge tube, and centrifuge to obtain a supernatant;

[0108] 2) Take 1 mL of the supernatant, add it again to a centrifuge tube containing 2 mL of methanol and 0.01 mL of acetic acid, and vortex to mix.

Embodiment 3

[0110] Pretreatment method of thyroid puncture fluid

[0111] 1) Add 30 mL of BD preservation solution containing puncture solution into a centrifuge tube, and centrifuge to obtain a supernatant;

[0112] 2) Take 0.5mL supernatant, add it again to a centrifuge tube containing 2mL propylene glycol and 0.02mL formic acid, and vortex to mix.

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Abstract

The invention provides a thyroid malignant tumor diagnosis system based on an open-type ion source. The system comprises (S1) a sample pretreatment kit which comprises an organic solvent, (S2) open-type ion source coupled mass spectrometry equipment, and (S3) optionally, a computer module and a processor used for constructing a machine learning model and obtaining the result of the sample to be tested. By means of mass spectrometry, characteristic molecules of malignant tumors can be given, and the diagnosis efficiency is greatly improved.

Description

technical field [0001] This application relates to a computer-aided diagnosis system, in particular to a system for diagnosing malignant tumors based on an open ion source, especially to a system for diagnosing malignant thyroid tumors based on an open ion source. Background technique [0002] Mass spectrometry (mass spectrometry for short) is a spectroscopic method juxtaposed with spectroscopy, and generally refers to a specialized technique widely used in various disciplines to identify compounds by preparing, separating, and detecting gas-phase ions. Mass spectrometry and spectroscopy, nuclear magnetic resonance and other methods are in a parallel relationship, and there are few cross-fields at present. In fact, the intersection between mass spectrometry and these classical spectroscopy methods is also a research field that deserves attention. A mass spectrometer generally consists of a sample introduction system, an ion source, a mass analyzer, and a detector. [0003]...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N27/62G06N20/10G16B25/10G16B40/00G16H50/20
CPCG01N27/62G16H50/20G16B40/00G16B25/10G06N20/10
Inventor 李晓东陈振贺曹磊钟定荣李洁王也
Owner SHIMADZU (CHINA) CO LTD